Regulation of osteoclast differentiation and function by the CaMK-CREB pathway

Keywords

CREB, NFAT, RANKL, Cell biology, Transcription factor

References

• The newly synthesized selective Ca2+/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells.Mariko Sumi, Kazutoshi Kiuchi, Tomohiko Ishikawa — 1991
• The versatility and universality of calcium signallingMichael J. Berridge, Peter Lipp, Martin D. Bootman — 2000
• T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γHiroshi Takayanagi, Kouetsu Ogasawara, Shigeaki Hida — 2000
• CREB regulates hepatic gluconeogenesis through the coactivator PGC-1Stephan Herzig, Fanxin Long, Ulupi S. Jhala — 2001
• Impaired Synaptic Plasticity and cAMP Response Element-Binding Protein Activation in Ca2+/Calmodulin-Dependent Protein Kinase Type IV/Gr-Deficient MiceNga Ho, Jason Liauw, Frank Blaeser — 2000
• NFAT and Osterix cooperatively regulate bone formationTakako Koga, Yūichi Matsui, Masataka Asagiri — 2005
• Nuclear Factor of Activated T Cells (NFAT)-dependent Transactivation Regulated by the Coactivators p300/CREB-binding Protein (CBP)Carmen García‐Rodríguez, Anjana Rao — 1998
• STO-609, a Specific Inhibitor of the Ca2+/Calmodulin-dependent Protein Kinase Kinase*Hiroshi Tokumitsu, Hiroyuki Inuzuka, Yumi Ishikawa — 2002
• Calmodulin and Calmodulin-dependent Kinase IIα Regulate Osteoblast Differentiation by Controlling c-fos Expression*Majd Zayzafoon, Keertik Fulzele, Jay M. McDonald — 2005
• Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.Hiroshi Takayanagi, Sunhwa Kim, Takako Koga — 2002
• Calcium/calmodulin‐dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neuronsViolaine Sée, Anne‐Laurence Boutillier, Haruhiko Bito — 2001
• CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression.Haruhiko Bito, Karl Deisseroth, Richard W. Tsien — 1996
• Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice.Alcino J. Silva, Charles F. Stevens, Susumu Tonegawa — 1992
• Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasisTakako Koga, Masanori Inui, Kazuya Inoue — 2004
• Calmodulin-dependent Protein Kinase IV Regulates Hematopoietic Stem Cell Maintenance*Christine M. Kitsos, Uma Sankar, Maddalena Illario — 2005
• Structure and regulation of calcium/calmodulin-dependent protein kinases.Thomas R. Soderling, James T. Stull — 2001
• Mechanism of the Generation of Autonomous Activity of Ca2+/Calmodulin-dependent Protein Kinase IV*Hiroshi Tokumitsu, Naoya Hatano, Hiroyuki Inuzuka — 2004
• A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss.Kazuhiro Aoki, Hiroaki Saito, Cécile Itzstein — 2006
• The regulation and function of c-fos and other immediate early genes in the nervous system.Morgan Sheng, Michael E. Greenberg — 1990
• Calmodulin is a critical regulator of osteoclastic differentiation, function, and survivalEric C. Seales, Keith Micoli, Jay M. McDonald — 2006

Cited by

• The role of T cells in osteoporosis, an update.Wen Zhao, Yuying Liu, Catherine M. Cahill — 2009
• Review Article Stem Cells, Phenotypic Inversion, and DifferentiationRobert W. Siggins, Ping 平 Zhang 张, David A. Welsh — 2008
• RANKL-induced schlafen2 is a positive regulator of osteoclastogenesis.Julian Voloj — 2008
• Inhibition of the classical NF-κB pathway prevents osteoclast bone-resorbing activity培新 董, Mihriban Karaayvaz, Nan Jia — 2009
• Osteoclast‐targeting small molecules for the treatment of neoplastic bone metastasesIac Mok, RF Tang — 2009
• Osteocyte Control of OsteoclastogenesisMarie Fleury — 2012
• Regulation of type 1 IP₃ receptor expression by dopamine D2-like receptors via AP-1 and NFATc4 activation.Herrera Arias, Byron Danilo — 2013
• [Osteoclast biology and osteoimmunology].Bhishm Tripathi — 2015
• Xanthotoxin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesisLetizia Mingardo — 2016
• Ubiquitin-dependent proteolysis of CXCL7 leads to posterior longitudinal ligament ossificationR.C. Visser — 2018
• Afamin stimulates osteoclastogenesis and bone resorption via Gi-coupled receptor and Ca2+/calmodulin-dependent protein kinase (CaMK) pathwaysBeom‐Jun Kim, Y.-S. Lee, S.-Y. Lee — 2013
• Stem cells, phenotypic inversion, and differentiation.Robert W. Siggins, Ping Zhang, David A. Welsh — 2008
• Calcium signaling in osteoclast differentiation and bone resorption.Hiroshi Kajiya — 2012
• Effects of the ω-3 Polyunsaturated Fatty Acid, EPA, in Suppressing Abdominal Aortic Aneurysm FormationWang Jack Hung-Wen — 2014
• Dopamine D1 receptors regulate type 1 inositol 1,4,5‐trisphosphate receptor expression via both AP‐1‐ and NFATc4‐mediated transcriptional processesKoji Mizuno, Kazuhiro Kurokawa, Seitaro Ohkuma — 2012
• New immune connections in osteoclast formationHiroshi Takayanagi — 2010
• The activation of type 1 corticotropin releasing factor receptor (CRF-R1) inhibits proliferation and promotes differentiation of neuroblastoma cells in vitro via p27(Kip1) protein up-regulation and c-Myc mRNA down-regulation.Giacomo Pozzoli, Maria Laura De Simone, Emilia Cantalupo — 2015
• New regulation mechanisms of osteoclast differentiationTomoki Nakashima, Hiroshi Takayanagi — 2011
• Calcium citrate: a new biomaterial that can enhance bone formation in situ.Liming Wang, Wei Wang, Xiucui Li — 2012
• The unexpected link between osteoclasts and the immune system.Hiroshi Takayanagi — 2010

Related papers

• Cyclic AMP response element‐binding (CREB)‐like proteins in a molluscan brain: cellular localization and learning‐induced phosphorylationMaria José Ribeiro, Zoltán Serfözö, Andrea Papp — 2003
• CREB-regulated transcription coactivator 2 (CRTC2; TORC2); cAMP responsive element binding protein 1 (CREB1; CREB)2010
• Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.Edith Hümmler, T J Cole, Julie A. Blendy — 1994
• Cyclic AMP-stimulated accumulation of the cAMP response element binding protein can occur without changes in gene expression.Sean M. Crosson, Gerald F. Davies, William J. Roesler — 1996
• The Notch intracellular domain represses CRE-dependent transcription.Rania Hallaq, Floriana Volpicelli, Inmaculada Cuchillo‐Ibáñez — 2015
• The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription.Terry E. Meyer, Gérard Waeber, Julia C. Lin — 1993
• The cAMP response element binding protein, CREB, is a potent inhibitor of diverse transcriptional activators.Frédéric P. Lemaigre, Chris I. Ace, Michael R. Green — 1993
• Endothelin-1- and depolarization-induced differential regulation of cAMP response element-binding protein in proliferating and developed vascular smooth muscle.Colin Gerard Egan, Graeme F. Nixon — 2004
• Calmodulin-dependent Protein Kinase II Potentiates Transcriptional Activation through Activating Transcription Factor 1 but Not cAMP Response Element-binding Protein*Atsushi Shimomura, Yasushi Ogawa, Takako Kitani — 1996
• The Regulation of CREB Signaling Pathway in Nervous System FunctionsSong Hai — 2013