Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives.
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Summary
This article describes how these neuroactive steroids modulate neurotransmitter receptors and addresses the neuropsychopharmacological potential that arises from the intracellular crosstalk between genomic and nongenomic steroid effects.
- Type
- review
- Published
- 1999-09-01
- Cited by
- 656
- References
- 53
- OpenAlex
- https://openalex.org/W2028466691
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:31429179
Keywords
Neuroactive steroid, Neuroscience, Crosstalk, Receptor, Neurotransmitter receptor
References
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- Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems.
- Progesterone therapy in women with complex partial and secondary generalized seizures
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Cited by
- Studies on neurosteroids XIX. Development and validation of liquid chromatography-tandem mass spectrometric method for determination of 5alpha-reduced pregnane-type neurosteroids in rat brain and serum.
- Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy.
- Vitamin D: the neglected neurosteroid?
- Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons.
- Two distinct inhibitory actions of steroids on cholinoceptor-mediated secretion of catecholamine from guinea-pig adrenal medullary cells.
- Neurostéroïdes et douleur
- Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity.
- Testosterone modulates Ca(v2.2) calcium channels' functional expression at rat levator ani neuromuscular junction.
- Protective effects of EUK4010 on β‐amyloid(1–42) induced degeneration of neuronal cells
- Translocator Protein (18 kDa) as a Target for Novel Anxiolytics with a Favourable Side‐Effect Profile
- Neuroactive Steroids and Affective Symptoms in Women Across the Weight Spectrum
- The Role of Estrogen and Estrogen Analogues in Friedreich’s Ataxia Cytoprotection
- Modulation différentielle de la transmission synaptique inhibitrice par la synthèse localisée de neurostéroïdes dans la corne dorsale de la moelle épinière de rat
- Neurosteroids and the Nervous System
- Physiological roles of endogenous neurosteroids at α2 subunit-containing GABAA receptors
- Intratympanic drug therapy with steroids for tinnitus control: a preliminary report.
- Neuroactive steroids and anxiety disorders.
- Causes and consequences of disturbances of cerebral glucose metabolism in sporadic Alzheimer disease: therapeutic implications.
- Challenge studies in anxiety disorders.
- Neuroprotective activities of estrogen: An update
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