Mechanisms in photodynamic therapy: part one-photosensitizers, photochemistry and cellular localization.
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Summary
The most important factor governing the outcome of PDT is how the PS interacts with cells in the target tissue or tumor, and the key aspect of this interaction is the subcellular localization of the PS.
- Type
- article
- Published
- 2004-12-01
- Cited by
- 1,763
- References
- 102
- Access
- Open access
- OpenAlex
- https://openalex.org/W2026889493
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32020592
Keywords
Photodynamic therapy, Singlet oxygen, Chemistry, Reactive oxygen species, Photosensitizer
References
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- Repetitive photodynamic therapy with topical delta-aminolaevulinic acid as an appropriate approach to the routine treatment of superficial non-melanoma skin tumours.
- Mitochondria-based photodynamic anti-cancer therapy.
- Characterization of lipid hydroperoxides generated by photodynamic treatment of leukemia cells
- Isolation and characterization of a new product produced by ionizing irradiation and type I photosensitization of 2'-deoxyguanosine in oxygen-saturated aqueous solution: (2S)-2,5'-ANHYDRO-1-(2'-deoxy-beta-D-erythro-pentofuranosyl)-5-guanidin ylidene- 2-hydroxy-4-oxoimidazolidine.
- Virtual Screening for SARS-CoV Protease Based on KZ7088 Pharmacophore Points
- Molecular diversity management strategies for building and enhancement of diverse and focused lead discovery compound screening collections.
- THE EFFECTS OF PHOTODYNAMIC THERAPY USING DIFFERENTLY SUBSTITUTED ZINC PHTHALOCYANINES ON VESSEL CONSTRICTION, VESSEL LEAKAGE AND TUMOR RESPONSE
- Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite.
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- Enzyme‐assisted Cell Photosensitization: A Proposal for an Efficient Approach to Tumor Therapy and Diagnosis. The Rose Bengal Fluorogenic Substrate
- Endoplasmic reticulum and Golgi apparatus are the preferential sites of Foscan® localisation in cultured tumour cells
- PRECLINICAL EXAMINATION OF FIRST and SECOND GENERATION PHOTOSENSITIZERS USED IN PHOTODYNAMIC THERAPY
Cited by
- Photodynamic Effect of Water Soluble Piperazinium and Imidazolium Salts of HPPH on A549 Cancer Cells
- Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: evidence from intracellular fluorescence and increased photodynamic efficacy in vitro.
- Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection
- Recent advances in biocompatible nanocarriers for delivery of chemotherapeutic cargoes towards cancer therapy.
- Oncologic photodynamic diagnosis and therapy: confocal Raman/fluorescence imaging of metal phthalocyanines in human breast cancer tissue in vitro.
- Targeted Nanodiamonds as Phenotype Specific Photoacoustic Contrast Agents for Breast Cancer
- Targeting Epigenetic Processes in Photodynamic Therapy-Induced Anticancer Immunity
- Semi-synthesis and PDT activities of a new amphiphilic chlorin derivative.
- Plasma membrane activatable polymeric nanotheranostics with self‐enhanced light‐triggered photosensitizer cellular influx for photodynamic cancer therapy
- Improved Photophysical and Photochemical Properties of Thiopheneethoxy Substituted Metallophthalocyanines on Immobilization onto Gold‐speckled Silica Nanoparticles
- Photodynamic therapy with topical photosensitizers in mucosal and semimucosal areas: Review from a dermatologic perspective.
- Nanopurpurin-based photodynamic therapy destructs extracellular matrix against intractable tumor metastasis.
- Verteporfin mediated sequence dependent combination therapy against ovarian cancer cell line.
- Molecular Design and Photophysical Characterization of Synthetic Bacteriochlorins for Solar Energy Conversion and Photodynamic Therapy
- Chapter 3: Antimicrobial properties of hydroxyxanthenes.
- Luminol luminescence-based theranostics for pre-clinical breast adenocarcinoma
- Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery
- BIOMEDICAL APPLICATION OF FULLERENES
- Synteza, badania strukturalne i fotochemiczne koniugatów porfirazyn i ftalocyjanin z adamantanem
- Fotochemiczna oraz fotodynamiczna aktywność wybranych porfirynoidów o potencjalnym działaniu przeciwnowotworowym inkorporowanych w nośniki liposomowe
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