Towards mild metal-catalyzed C-H bond activation.
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Summary
This critical review summarizes and discusses endeavours towards the development of mild C-H activation methods and wishes to trigger more research towards this goal.
- Type
- review
- Published
- 2011-08-15
- Cited by
- 2,061
- References
- 132
- OpenAlex
- https://openalex.org/W2024983608
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205788363
Keywords
Scope (computer science), Combinatorial chemistry, Catalysis, Surface modification, Chemistry
References
- Versatile Pd(OTf)2 x 2 H2O-catalyzed ortho-fluorination using NMP as a promoter.
- A palladium-catalyzed oxidative cycloaromatization of biaryls with alkynes using molecular oxygen as the oxidant.
- Rh(III)-catalyzed directed C-H olefination using an oxidizing directing group: mild, efficient, and versatile.
- Asymmetric synthesis of (-)-incarvillateine employing an intramolecular alkylation via Rh-catalyzed olefinic C-H bond activation.
- Ruthenium-catalyzed direct arylations through C-H bond cleavages.
- Pd-catalyzed C-H bond functionalization on the indole and pyrrole nucleus.
- Enantioselective Intramolecular Hydroarylation of Alkenes via Directed C–H Bond Activation
- Ligand-Enabled Reactivity and Selectivity in a Synthetically Versatile Aryl C–H Olefination
- Palladium-catalyzed benzylic addition of 2-methyl azaarenes to N-sulfonyl aldimines via C-H bond activation.
- Rh(III)-catalyzed oxidative olefination of vinylic C-H bonds: efficient and selective access to di-unsaturated α-amino acid derivatives and other linear 1,3-butadienes.
- Cu(II)-catalyzed direct and site-selective arylation of indoles under mild conditions.
- Room Temperature C–H Activation and Cross-Coupling of Aryl Ureas in Water
- Constructing Multiply Substituted Arenes Using Sequential Pd(II)-Catalyzed C–H Olefination
- The selective functionalization of saturated hydrocarbons: Gif chemistry
- On the Mechanism of Palladium-Catalyzed Aromatic C–H Oxidation
- Analysis of the concerted metalation-deprotonation mechanism in palladium-catalyzed direct arylation across a broad range of aromatic substrates.
- Hydroheteroarylation of alkynes under mild nickel catalysis.
- Transition metal-catalyzed C-H activation reactions: diastereoselectivity and enantioselectivity.
- Intramolecular Pd(II)-catalyzed oxidative biaryl synthesis under air: reaction development and scope.
- New method for preparation of coumarins and quinolinones via Pd-catalyzed intramolecular hydroarylation of C-C triple bonds.
Cited by
- Pd-catalysed synthesis of isoquinolinones and analogues via C-H and N-H bonds double activation.
- Synthesis of functionalized fluorescent indenes from electron-rich α-aryl ketonitriles.
- Regioselective threefold aromatic substitution of benzoic acid derivatives by dearomatization, regioselective functionalization, and rearomatization.
- Rhodium(III)-catalyzed C-H olefination for the synthesis of ortho-alkenyl phenols using an oxidizing directing group.
- Purinyl N1-Directed Aromatic C–H Oxidation in 6-Arylpurines and 6-Arylpurine Nucleosides
- "On water", phosphine-free palladium-catalyzed room temperature C-H arylation of indoles.
- Strategies to prepare and use functionalized organometallic reagents.
- Efficient silver-catalyzed direct sulfenylation and selenylation of rich arenes.
- Rhodium(III)-catalyzed C-H activation and intermolecular annulation with terminal alkynes: from indoles to carbazoles.
- Palladium(II)-catalysed ortho-arylation of N-benzylpiperidines.
- Regiospecific Benzoylation of Electron-Deficient N-Heterocycles with Methylbenzenes via a Minisci-Type Reaction.
- Cobalt(III)-Catalyzed Aryl and Alkenyl C-H Aminocarbonylation with Isocyanates and Acyl Azides.
- Cu(II)-Mediated C(sp(2))-H Hydroxylation.
- Copper-Mediated Aerobic Oxidative Synthesis of 3-Bromo-imidazo[1,2-a]pyridines with Pyridines and Enamides.
- Copper-Catalyzed 8-Amido Chelation-Induced Remote C-H Amination of Quinolines.
- [N,P]-pyrrole PdCl2 complexes catalyzed the formation of dibenzo-α-pyrone and lactam analogues.
- Oxidative Annulation of Arenecarboxylic and Acrylic Acids with Alkynes under Ambient Conditions Catalyzed by an Electron-Deficient Rhodium(III) Complex.
- Traceless directing group mediated branched selective alkenylation of unbiased arenes.
- New complexity for aromatic ring agostic interactions.
- Visible Light as a Sole Requirement for Intramolecular C(sp3)-H Imination.
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