Immunodesign of experimental sepsis by cecal ligation and puncture
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Summary
Standardized procedures for inducing sepsis in mice and rats are defined by applying defined severity grades of sepsi through modulation of the position of cecal ligation.
- Type
- article
- Published
- 2008-12-11
- Cited by
- 2,066
- References
- 25
- Access
- Open access
- OpenAlex
- https://openalex.org/W2023945291
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40394225
Keywords
Sepsis, Ligation, Medicine, Bacteremia, Animal model
References
- Distance of Cecum Ligated Influences Mortality, Tumor Necrosis Factor-Alpha and Interleukin-6 Expression following Cecal Ligation and Puncture in the Rat
- Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model.
- Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture.
- Characterization of a hyperdynamic murine model of resuscitated sepsis using echocardiography.
- Fluid resuscitation improves survival of endotoxemic or septicemic rats: possible contribution of tumor necrosis factor.
- Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003*
- FLUID RESUSCITATION AND ANTIBIOTICS ENHANCE SURVIVAL BY UNKNOWN MECHANISMS
- RODENT MODELS OF INTRA-ABDOMINAL INFECTION
- CECAL LIGATION AND PUNCTURE
- Sepsis and septic shock--a review of laboratory models and a proposal.
- ANTIBIOTIC TREATMENT INFLUENCES OUTCOME IN MURINE SEPSIS: MEDIATORS OF INCREASED MORBIDITY
- Functional roles for C5a receptors in sepsis
- TNFR1 SIGNALING RESISTANCE IN FEMALE MYOCARDIUM IS MEDIATED BY GENDER DIFFERENCES IN THE STAT3/SOCS3 PATHWAY
- Genetic background determines susceptibility during murine septic peritonitis.
- The chronic consequences of severe sepsis
- Cecum location in rats and the implications for intraperitoneal injections
- Interleukin-10 Controls the Onset of Irreversible Septic Shock
- The disconnect between animal models of sepsis and human sepsis
- Deaths: preliminary data for 2002.
- Cecal ligation and puncture with total parenteral nutrition: a clinically relevant model of the metabolic, hormonal, and inflammatory dysfunction associated with critical illness.
Cited by
- The role of TNF receptor type 2 on myeloid cells in sepsis - functional analysis
- Fecal peritonitis in rats.
- The monomer‐dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue‐specific neutrophil recruitment
- Long-term Dynamic Profiling of Inflammatory Mediators in Double-hit Burn and Sepsis Animal Models
- Pretreatment with interleukin-6 small interfering RNA can improve the survival rate of polymicrobial cecal ligation and puncture mice by down regulating interleukin-6 production.
- Sustained and incomplete recovery of naïve CD8+ T-cell precursors after sepsis contributes to impaired CD8+ T-cell responses to infection
- Boosted Rat Natural Xenoantibodies Cross-React with Enterococcus faecalis by Targeting Melibiose and L-Rhamnose
- Glutamine Administration Modulates Lung &ggr;&dgr; T Lymphocyte Expression in Mice With Polymicrobial Sepsis
- The first cyclomegastigmane rhododendroside A from Rhododendron brachycarpum alleviates HMGB1-induced sepsis
- Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1.
- Acute phase protein α1-antitrypsin reduces the bacterial burden in mice by selective modulation of innate cell responses.
- Preconditioning mice with activators of AMPK ameliorates ischemic acute kidney injury in vivo.
- Glucose-Insulin-Potassium Alleviates Intestinal Mucosal Barrier Injuries Involving Decreased Expression of Uncoupling Protein 2 and NLR Family-Pyrin Domain-Containing 3 Inflammasome in Polymicrobial Sepsis
- Myosin Light Chain Kinase Knockout Improves Gut Barrier Function and Confers a Survival Advantage in Polymicrobial Sepsis
- Glutamine Administration in Early or Late Septic Phase Downregulates Lymphocyte PD‐1/PD‐L1 Expression and the Inflammatory Response in Mice With Polymicrobial Sepsis
- Klotho ameliorates sepsis-induced acute kidney injury but is irrelevant to autophagy
- Human Adipose Tissue-Derived Stromal Cells Attenuate the Multiple Organ Injuries Induced by Sepsis and Mechanical Ventilation in Mice
- UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
- Fibronectin extra domain a limits liver dysfunction and protects mice during acute inflammation
- Discovery and investigation of a novel role for mitochondrial prohibitin in mitigating acute heart failure in endotoxic shock
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