The ligation amplification reaction (LAR)--amplification of specific DNA sequences using sequential rounds of template-dependent ligation.

Keywords

Ligation, Oligonucleotide, Biology, Multiplex ligation-dependent probe amplification, Sequencing by ligation

References

• Simultaneous analysis of multiple polymorphic loci using amplified sequence polymorphisms (ASPs).José Ignacio Escobar Y Kirkpatrick — 1988
• Direct Analysis of Single Nucleotide Variation in Human DNA and RNA Using In Situ Dot HybridizationDan Y. Wu, G. Nozari, Monica Schöld — 1989
• Oligonucleotide directed mutagenesis of the human beta-globin gene: a general method for producing specific point mutations in cloned DNA.R. Bruce Wallace, Monica Schöld, Merrie Jo Johnson — 1981
• Detection of sickle cell anaemia and thalassaemiasFarid Chehab, Marie Doherty, Shi‐Ping Cai — 1987
• Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides.Brenda J. Conner, Antonio A. Reyes, C Morin — 1983
• Regulation of inter- and intramolecular ligation with T4 DNA ligase in the presence of polyethylene glycol.Ken’ichiro Hayashi, Masako Nakazawa, Yukuo Ishizaki — 1986
• Diagnosis of sickle cell anemia and beta-thalassemia with enzymatically amplified DNA and nonradioactive allele-specific oligonucleotide probes.Randall K. Saiki, C. C. Chang, Corey Levenson — 1988
• Analysis of DNA extracted from formalin-fixed, paraffin-embedded tissues by enzymatic amplification and hybridization with sequence-specific oligonucleotides.Chaka C. Impraim, Randall K. Saiki, Henry A. Erlich — 1987
• Dot blot detection of point mutations with adjacently hybridising synthetic oligonucleotide probes.A M Alves, Francis J. Carr — 1988
• Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probesRandall K. Saiki, Teodorica L. Bugawan, Glenn T. Horn — 1986
• Specificity of the nick-closing activity of bacteriophage T4 DNA ligase.Dan Y. Wu, R. Bruce Wallace — 1989
• Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.Randall K. Saiki, David H. Gelfand, Susanne Stoffel — 1988
• Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.Christine J. Farr, Randall K. Saiki, H A Erlich — 1988
• The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit beta-globin DNA.R. Bruce Wallace, Merrie Jo Johnson, Tadaaki Hirose — 1981
• Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.Randall K. Saiki, Stephen J. Scharf, Fred Faloona — 1985
• Detection of specific sequences among DNA fragments separated by gel electrophoresis.E.M. Southern — 1975
• Polymer-stimulated ligation: enhanced blunt- or cohesive-end ligation of DNA or deoxyribooligonucleotides by T4 DNA ligase in polymer solutions.Barbara H. Pheiffer, Steven B. Zimmerman — 1983
• A ligase-mediated gene detection technique.Ulf Landegren, Robert Kaiser, Jane Z. Sanders — 1988

Cited by

• Simultaneous analysis of multiple polymorphic loci using amplified sequence polymorphisms (ASPs).José Ignacio Escobar Y Kirkpatrick — 1988
• High-density multiplex detection of nucleic acid sequences: oligonucleotide ligation assay and sequence-coded separation.李满荣 毛少瑜 — 1994
• Nonradioactive labeling and high-sensitive detection of PCR productsJ. Demazière — 1994
• High sequence fidelity in a non-enzymatic DNA autoligation reaction.Rhonda DeLong, Suk H. Kim — 1999
• L-RCA (ligation-rolling circle amplification): a general method for genotyping of single nucleotide polymorphisms (SNPs).Ewa Stańczyk-Hugiet — 2001
• Snipping polymorphisms from large EST collections in barley (Hordeum vulgare L.)Ashim K. Datta, Devraj Mandal, Kalpana Sahoo — 2003
• Recent developments in ligase-mediated amplification and detection.志穂 松尾, 紀美恵 中村, 涼子 本郷 — 2004
• A colorimetric method for point mutation detection using high-fidelity DNA ligaseCarlos García — 2005
• A New Genotyping Method for Detecting Low Abundance Single Nucleotide Mutations Based on Gap Ligase Chain Reaction and Quantitative PCR AssayВласова Татьяна Михайловна — 2011
• Detection and Sequencing of Amplified Single MoleculesRongqin Ke — 2012
• Commercialization of nucleic acid probe technology: current status.James H. Godsey, Kurt M. Vanden Brink, Luke J. DiMichele — 1994
• Genetic Variation of Apolipoprotein B in the Finns: Effects of Serum Lipid LevelsMarja Ilmonen — 2000
• New approaches for diagnosis of infections by intracellular bacteria.R. Marre — 2000
• New strategies for the accurate identification and detection of plant pathogensAcademisch Proefschrift, R. V. Doorn — 2012
• MOLEKULARNA DIJAGNOSTIKA ORALNIH INFEKCIJAMagdalena Grce — 2014
• Bacterial Invasion into Eukaryotic CellsTobias A. Oelschlaeger, Jörg Hacker — 2000
• Single nucleotide polymorphisms : methods and protocolsPui–Yan Kwok — 2002
• Molecular diagnostics of infectious diseases.Malin Nygren — 2000
• AIDS TestingGerald Schochetman, J. Richard George — 1994
• Nonradioactive Labeling and Detection of BiomoleculesChristoph Keßler — 1992

Related papers

• [Ligase chain reaction (LCR)].K Yamanishi, Hirokazu Yasuno — 1993
• Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification.Jan P. Schouten — 2002
• Template‐independent ligation of single‐stranded DNA by T4 DNA ligaseHeiko Kuhn, Maxim D. Frank‐Kamenetskii — 2005
• [Development of novel clinical tests and their contribution to laboratory diagnosis--ligase chain reaction].Ryuichi Yajima — 1997
• Detection of point mutations with a modified ligase chain reaction (Gap-LCR).Klara Abravaya, John J. Carrino, Sharon Muldoon — 1995
• A new approach for point mutation detection based on a ligase chain reaction.Anna V Demchinskaya, И. А. Шилов, A. S. Karyagina — 2001
• DNA ligases and ligase-based technologiesWeiguo Cao — 2001
• Enzyme-regulated activation of DNAzyme: a novel strategy for a label-free colorimetric DNA ligase assay and ligase-based biosensing.Kaiyu He, Wang Li, Zhou Nie — 2012