The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer

Keywords

Cyclin-dependent kinase, Cell cycle, Kinase, Cell biology, Biology

References

• Cellular effects of olomoucine, an inhibitor of cyclin‐dependent kinasesMarcos Sánchez — 1995
• The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.Qianjin Hu, Nicholas J. Dyson, Ed Harlow — 1990
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• Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein.Stewart Bates, David Parry, Laura Bonetta — 1994
• Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis.Ingrid Hoffmann, Paul R. Clarke, María Jesús Marcote — 1993
• Deregulation of cyclin E in breast cancer.Khandan Keyomarsi, Darryl Conte, Wendy M. Toyofuku — 1995
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• Inhibitors of the Cip/Kip family.Ludger Hengst, Steve I. Reed — 1998
• p53-induced p21 controls DNA replication.S Waga, R. Li, Bruce Stillman — 1997
• An exogenous cdk inhibitor, butyrolactone-I, induces apoptosis with increased Bax/Bcl-2 ratio in p53-mutated pancreatic cancer cells.Michihiko Wada, Ryo Hosotani, Jeon Uk Lee — 1998
• Use and specificity of staurosporine, UCN-01, and calphostin C as protein kinase inhibitors.Tatsuya Tamaoki — 1991
• Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II.Paula Rickert, Wolfgang Seghezzi, Fergus Shanahan — 1996
• The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other propertiesJulia R. Gage, Craig Meyers, F O Wettstein — 1990
• Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol.Bernard W. Parker, Gurmeet Kaur, Wilberto Nieves‐Neira — 1998
• Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer.Vincenzo Esposito, Alfonso Baldi, Antonio De Luca — 1997
• The lamin B receptor of the inner nuclear membrane undergoes mitosis-specific phosphorylation and is a substrate for p34cdc2-type protein kinase.Jean‐Claude Courvalin, Neil Segil, Günter Blobel — 1992
• ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathwayDae‐Sik Lim, Seong‐Tae Kim, Bo Xu — 2000

Cited by

• Development of an shRNA screen to identify mediators of cellular senescence in human breast epithelial cellsK. Wanek — 2011
• Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells.Zhuo Chen, De‐Quan Li, Louis Tong — 2006
• Effect of HIV-1 Vpr on Cell Cycle RegulatorsSjouke de Zee — 2004
• Toward a global characterization of the phosphoproteome in prostate cancer cells: Identification of phosphoproteins in the LNCaP cell lineFrancesco Giorgianni, Yingxin Zhao, Dominic M. Desiderio — 2007
• A new, unexpected action of olomoucine, a CDK inhibitor, on normal human cells: Up‐regulation of CLIMP‐63, a cytoskeleton‐linking membrane proteinMichael B. Teitz, Stephen R. Rosenthal — 2007
• Review Article Insights into Endometrial Serous Carcinogenesis and ProgressionOluwole Fadare, Wenxin Zheng — 2009
• The inference of breast cancer metastasis through gene regulatory networksBrandon Frost — 2012
• American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators.Brett W. Hawkins, Paul K. Villar — 2012
• Pin1 acts as a negative regulator of the G2/M transition by interacting with the Aurora-A–Bora complexJavier Plaza Penadés — 2013
• Restriction Endonucleases from Invasive Neisseria gonorrhoeae Cause Double-Strand Breaks and Distort Mitosis in Epithelial Cells during InfectionLucy Britner — 2014
• Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data憲治 高田 — 2016
• Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cellsJim Walker, John Lawler — 2017
• ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitroTibor K. Pogány — 2017
• The receptor for activated protein kinase C promotes cell growth, invasion and migration in cervical cancer博子 米元 — 2017
• DDX21 promotes gastric cancer proliferation by regulating cell cycle.Jorge M. Santamaría, W. J. Davies, C. J. Atkinson — 2018
• In vitro study of Withanolide D toxicity on goat preantral follicles and its effects on the cell cycle.Denise Damasceno Guerreiro, Laritza Ferreira de Lima, Naíza Arcângela Ribeiro de Sá — 2019
• Efeitos da capsaicina em células estreladas hepáticasShanna Bitencourt — 2012
• Gene Repression and Cell Cycle Regulation by PU.1 in Acute Myeloid LeukemiaRachel Gh Ziliotto — 2013
• Biological evaluation of chlorogold complexes as potential anti-tumoural compounds: unraveling mechanisms of actionPedro Freire de Sousa Martins — 2014
• Incorporation of bacterial quorum sensing in synthetic biologyHsuan‐Chen Wu — 2012

Related papers

• Regulation of the G1 phase of the mammalian cell cycleDubravka Donjerković, David W. Scott — 2000
• [The cell cycle and the tumor suppressor genes].Hideki Kobayashi — 1996
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• CDK redundancy guarantees cell cycle progression in RB-negative tumor cells independently of their p16 statusMarta Santamariña, Gonzalo Hernández, Juan Zalvide — 2008
• Seek and Destroy: SCF Ubiquitin Ligases in Mammalian Cell Cycle ControlCharles Spruck, Heimo Strohmaier — 2002
• Cell Cycle and Cancer: The G1 Restriction Point and the G1 / S TransitionSagrario Ortega, Marcos Malumbres, Mariano Barbacid — 2002
• Multiple functions of p27Kip1 and its alterations in tumor cells: a reviewAlessandro Sgambato, Achille Cittadini, Beatrice Faraglia — 2000
• Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytesEduardo Firpo, Andrew Koff, Michael J. Solomon — 1994