Caenorhabditis elegans 2007: the premier model for the study of aging.
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Summary
This is the 25th anniversary of the discovery of extended longevity mutants in Caenorhabditis elegans and many themes were pursued including dietary restriction, daf-9 action, the role of proteolysis and autophagy, and the continued search for more Age mutants.
- Type
- review
- Published
- 2007-10-01
- Cited by
- 71
- References
- 27
- Access
- Open access
- OpenAlex
- https://openalex.org/W2014737421
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39825305
Keywords
Caenorhabditis elegans, Longevity, Biology, Mutant, Model organism
References
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- Longevity determined by developmental arrest genes in Caenorhabditis elegans
- Two neurons mediate diet-restriction-induced longevity in C. elegans
- Caloric Restriction and Autophagy in Caenorhabditis elegans
- Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans
- Hormesis and aging in Caenorhabditis elegans.
- The role of NAD+ dependent histone deacetylases (sirtuins) in ageing.
- Microarray analysis of variation in individual aging C. elegans: approaches and challenges.
- A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
- Autophagy Regulates Ageing in C. elegans
- Dietary deprivation extends lifespan in Caenorhabditis elegans
- Adult‐Limited Dietary Restriction Slows Gompertzian Aging in Caenorhabditis elegans
- Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
Cited by
- Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans
- Reproductive experience may positively adjust the trajectory of senescence.
- Changes in DNA methylation patterns in mammals with senescence, ageing and energy restriction
- Funktionelle Analyse der C. elegans Gene vang-1, atad-3 und mics-1 in Bezug auf Alterung und Stressresistenz
- Microchip analysis device for fixed Caenorhabditis elegans by tapered micro channel
- Hypoxia-inducible regulatory networks and their roles in aging in C. elegans
- Photobiomodulation in animal models of ageing and Alzheimer's disease
- The ecological genetics of senescence and stress resistance in Caenorhabditis elegans
- Rôle des protéines 14-3-3 dans la régulation de la longévité par la voie DAF-2/Insuline/IGF-1 chez Caenorhabditis elegans
- Clinical Experience of a Diet Designed to Reduce Aging
- Global aging and the brain.
- FOXO in aging: Did evolutionary diversification of FOXO function distract it from prolonging life?
- Aging genetics and aging.
- SIRT1 and Caloric Restriction: An Insight Into Possible Trade-Offs Between Robustness and Frailty
- The interplay between mitochondria and autophagy and its role in the aging process.
- Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in a sir2.1-dependent Manner in Caenorhabditis elegans*
- Micro fluidic device to analyze the effect of cadmium on Caenorhabditis elegans
- Healthy Aging – Insights from Drosophila
- Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging
- Current metabolomics: practical applications.
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