Liposome-delivered Zn(II)-2,3-naphthalocyanines as potential sensitizers for PDT: synthesis, photochemical, pharmacokinetic and phototherapeutic studies.
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Summary
The aim of this investigation is to report the synthesis and fundamental photochemical properties of naphthalocyanines with potential interest for photodynamic therapy (PDT), as well as their pharmacokinetics and phototherapeutic effects in a tumor model.
- Type
- article
- Published
- 1993-12-01
- Cited by
- 67
- References
- 32
- OpenAlex
- https://openalex.org/W2014535074
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24395714
Keywords
Photosensitizer, Liposome, Photodynamic therapy, Chemistry, Photochemistry
References
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- PHTHALOCYANINES AS PHOTODYNAMIC SENSITIZERS *
- Autoradiographic distribution of hematoporphyrin derivative in normal and tumor tissue of the mouse.
- Polymeric bound porphyrines and their precursors, 3. Photoredox properties of combined moieties of porphyrine and phthalocyanine, covalently bound to polystyrene
- Polymeric bound porphyrins and their precursors, 6. Syntheses of water‐soluble, negatively or un‐charged polymers with covalently bound moieties of porphyrin derivatives
- Photodynamic therapy in lung and gastrointestinal cancers.
- PHOTOTOXIC AND PHOTOCHEMICAL PROPERTIES OF SANGUINARINE *
- Potential new photosensitizers for photodynamic therapy
- Quantum yield of singlet molecular oxygen sensitization by copper(II) tetracarboxyphthalocy anine
- BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES‐XL PHOTOTOXICITY OF SULFONATED ALUMINUM NAPHTHALOCYANINES TOWARDS V‐79 CHINESE HAMSTER CELLS
- Redox chemistry of dioxygen species
- Photophysical properties and photodynamic activity in vivo of some tetrapyrroles.
- Water-soluble metal naphthalocyanines--near-IR photosensitizers: cellular uptake, toxicity and photosensitizing properties in NHIK 3025 human cancer cells.
- STUDIES ON THE MECHANISM OF THE HEMATOPORPHYRIN‐SENSITIZED PHOTOOXIDATION OF 1,3‐DIPHENYLISOBENZOFURAN IN ETHANOL and UNILAMELLAR LIPOSOMES
- Preferential delivery of liposome-incorporated porphyrins to neoplastic cells in tumour-bearing rats.
- Porphyrins, Phthalocyanines, and Naphthalocyanines for Various Processes of Visible Light Driven Conversion Processes
- PHOTOSENSITIZERS: THERAPY AND DETECTION OF MALIGNANT TUMORS
- The photophysics and photostability of zinc(II) and aluminium(III) sulphonated naphthalocyanines
- Liposome- or LDL-administered Zn (II)-phthalocyanine as a photodynamic agent for tumours. I. Pharmacokinetic properties and phototherapeutic efficiency.
- Silicon naphthalocyanine triplet state and oxygen. A reversible energy-transfer reaction
Cited by
- Photo-oxidative Stability and its Correlation with Semi-empirical MO Calculations of Various Tetraazaporphyrin Derivatives in Solution
- Photodynamic Therapy and the Development of Metal-Based Photosensitisers
- Yield of intersystem (singlet–triplet) crossing in phthalocyanines evaluated on the basis of a time in resolved photothermal method
- PHOTOOXIDATION OF 2‐MERCAPTOETHANOL BY VARIOUS WATER‐SOLUBLE PHTHALOCYANINES IN AQUEOUS ALKALINE SOLUTION UNDER IRRADIATION WITH VISIBLE LIGHT
- Effect of delivery system on the pharmacokinetic and phototherapeutic properties of bis(methyloxyethyleneoxy) silicon-phthalocyanine in tumor-bearing mice.
- Phthalocyanines and related compounds: XLIII. Synthesis of poly[phenyl(alkyl)sulfanyl]-substituted phthalonitriles and some phthalocyanines based thereon
- Effect of chirality on cellular uptake, imaging and photodynamic therapy of photosensitizers derived from chlorophyll-a
- Self-assembly of drug-loaded liposomes on genetically engineered target-recognizing M13 phage: a novel nanocarrier for targeted drug delivery.
- The synthesis and in vitro photodynamic activity of a series of novel ruthenium(II)-2,3-naphthalocyanines
- Metal chelates of porphyrin derivatives as sensitizers in photooxidation processes of sulfur compounds and in photodynamic therapy of cancer
- Synthesis of Phthalocyanines with One Sulfonic Acid, Carboxylic Acid, or Amino Group
- Nanomaterials formulations for photothermal and photodynamic therapy of cancer
- PHOTODYNAMIC ACTIVITIES and SKIN PHOTOSENSITIVITY OF THE bis(DIMETHYLTHEXYLSILOXY)SILICON 2,3‐NAPHTHALOCYANINE IN MICE
- Experimental PDT: studies on new Si-phthalocyanines and Si-naphthalocyanines in Cremophor emulsions
- The importance of liposomes as models and tools in the understanding of photosensitization mechanisms.
- Light intensity effect on the mechanisms of tumor damage photosensitized by a substituted Zn(II)-naphthalocyanine
- Si(IV)-methoxyethylene-glycol-naphthalocyanine: synthesis and pharmacokinetic and photosensitizing properties in different tumour models.
- Triazolephthalocyanines: synthesis, supramolecular organization and physical properties
- In vitro photodynamic effects of phthalocyaninatosilicon covalently linked to 2,2,6,6-tetramethyl-1-piperidinyloxy radicals on cancer cells.
- Hydrophobic Zn(II)-naphthalocyanines as photodynamic therapy agents for Lewis lung carcinoma.
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