Tissue injury caused by deposition of immune complexes is L-arginine dependent.

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Summary

The arginine analogue, NG-monomethyl-L-arginine (N-MeArg), which blocks NO, protects against immune complex-induced vascular injury in rats and suggests that in vivo metabolic products of L- arginine, such as NO(.), are directly or indirectly linked to immunecomplex-induced tissue injury.

Type
article
Published
1991-07-15
Cited by
435
References
0
Access
Open access

Keywords

Peroxynitrite, Arginine, Immune system, Nitric oxide, Chemistry

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