Integrins: a family of cell surface receptors.
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Summary
This brief review of sequence data from embryogenesis, thrombosis, and lymphocyte help and killing is summarized and attempts to clarify the relationships among the members of this family of cell surface receptors.
- Type
- review
- Published
- 1987-02-27
- Cited by
- 4,152
- References
- 49
- OpenAlex
- https://openalex.org/W2013381560
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27274629
Keywords
Biology, Integrin, Receptor, Cell biology, Cell surface receptor
References
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- Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.
- cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide.
- Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to "integrin".
- cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.
- A monoclonal antibody to human platelet glycoprotein IIIa detects a related protein in cultured human endothelial cells.
- Sequence homology of the LFA-1 and Mac-1 leukocyte adhesion glycoproteins and unexpected relation to leukocyte interferon
- A monoclonal antibody identifies a glycoprotein complex involved in cell-substratum adhesion.
- Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion
- Tissue-specific modulation of a set of related cell surface antigens in Drosophila
- Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex
- Cloning of the beta subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family.
- Development of cell surface linkage complexes in cultured fibroblasts
- Interaction of fibronectin with its receptor on platelets.
- Arg-Gly-Asp: a versatile cell recognition signal.
- Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp--specific adhesion receptors.
- Variants of the cell recognition site of fibronectin that retain attachment-promoting activity.
Cited by
- Thrombospondin as a component of the extracellular matrix of epiretinal membranes: Comparisons with cellular fibronectin
- Intercellular adhesion molecule-1 (ICAM-1) and leukocyte function-associated antigen-1 (LFA-1) expression in human epiretinal membranes
- Integrins: versatility, modulation, and signaling in cell adhesion.
- Eicosanoids, other fatty acid metabolites and the cardiovascular system: are the present antithrombotic approaches rational?
- Steroid modulation of the expression of growth factors and oncogenes in breast cancer.
- Cross‐linking of VLA/CD29 molecule has a co‐mitogenic effect with anti‐CD3 on CD4 cell activation in serum‐free culture system
- Histiocytosis X arising in Hodgkin's disease: immunophenotypic characterization with a panel of monoclonal antibodies
- Enhancement of vitronectin expression in human HepG2 hepatoma cells by transforming growth factor-beta 1.
- An RGD spacing of 440 nm is sufficient for integrin alpha V beta 3- mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation
- Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin
- Contribution of CR3, CD11b/CD18 to cytolysis by human NK cells.
- Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg).
- Accessory Cell Signals Involved in T‐Cell Activation
- Low expression of collagen receptors in moderate and poorly differentiated colorectal adenocarcinomas.
- Microvascular endothelial cell heterogeneity: Interactions with leukocytes and tumor cells
- Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells
- Drosophila adhesion molecules and neural development.
- Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex
- Coordinate induction of fibronectin, fibronectin receptor, tropomyosin, and actin genes in serum-stimulated fibroblasts.
- The osteoblast-like differentiated phenotype of a variant of MG-63 osteosarcoma cell line correlated with altered adhesive properties.
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