Achieving Donor-Specific Hyporesponsiveness Is Associated with FOXP3+ Regulatory T Cell Recruitment in Human Renal Allograft Infiltrates1
Explore this paper's citation graph
Summary
Reaching donor-specific hyporesponsiveness is feasible after renal transplantation and associated with Treg recruitment in the graft, suggesting that the recruitment of Tregs in the allograft plays an important role for renal acceptance.
- Type
- article
- Published
- 2007-10-01
- Cited by
- 161
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W1565046736
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21182862
Keywords
FOXP3, Immunology, Medicine, Immune system
References
- Induction of foxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants1
- In vivo dynamics of regulatory T-cell trafficking and survival predict effective strategies to control graft-versus-host disease following allogeneic transplantation.
- Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.
- Lymphocyte immunophenotyping by flow cytometry in normal adults. Comparison of fresh whole blood lysis technique, Ficoll-Paque separation and cryopreservation.
- Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes.
- Transplantation tolerance from a historical perspective
- Alemtuzumab Induction and Sirolimus Plus Mycophenolate Mofetil Maintenance for CNI and Steroid‐Free Kidney Transplant Immunosuppression
- Contrasting Effects of Cyclosporine and Rapamycin in De Novo Generation of Alloantigen‐Specific Regulatory T Cells
- Metastable Tolerance to Rhesus Monkey Renal Transplants Is Correlated with Allograft TGF-β1+CD4+ T Regulatory Cell Infiltrates1
- Immunocompetent T‐Cells with a Memory‐Like Phenotype are the Dominant Cell Type Following Antibody‐Mediated T‐Cell Depletion
- Accelerated Memory Cell Homeostasis during T Cell Depletion and Approaches to Overcome It
- Selective Survival of Naturally Occurring Human CD4+CD25+Foxp3+ Regulatory T Cells Cultured with Rapamycin1
- CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody1
- Antigen localization and migration in immunity and tolerance.
- Donor-Specific Antibodies in Allograft Rejection: Clinical and Experimental Data
- Peripheral blood lymphoid subsets and long-term clinical course of kidney recipients: a longitudinal study.
- Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery1
- Enzyme-Linked Immunosorbent Spot Assay for Donor-Reactive Interferon-Gamma-Producing Cells Identifies T-Cell Presensitization and Correlates with Graft Function at 6 and 12 Months in Renal-Transplant Recipients
- Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys.
- Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys
Cited by
- In Kidney Transplant Patients, Alemtuzumab but Not Basiliximab/Low-Dose Rabbit Anti-Thymocyte Globulin Induces B Cell Depletion and Regeneration, Which Associates with a High Incidence of De Novo Donor-Specific Anti-HLA Antibody Development
- Tolerogenic dendritic cell therapy in organ transplantation
- Learning to Live Together: Harnessing Regulatory T cells to Induce Organ Transplant Tolerance
- Immunosuppression in the era of biological agents.
- Dynamic changes of regulatory T cell and dendritic cell subsets in stable kidney transplant patients: a prospective analysis.
- Costimulatory blockade with mTor inhibition abrogates effector T‐cell responses allowing regulatory T‐cell survival in renal transplantation
- Are We Ready for the Use of Foxp3+ Regulatory T Cells for Immunodiagnosis and Immunotherapy in Kidney Transplantation?
- ATG‐Fresenius Treatment and Low‐Dose Tacrolimus: Results of a Randomized Controlled Trial in Liver Transplantation
- Two‐year follow‐up of a prospective study of circulating regulatory T cells in renal transplant patients
- FOXP3 Expression in Human Kidney Transplant Biopsies Is Associated with Rejection and Time Post Transplant but Not with Favorable Outcomes
- A Five-Gene Peripheral Blood Diagnostic Test for Acute Rejection in Renal Transplantation
- Monitorización de las células T reguladoras circulantes en trasplante
- Clinical significance of the ratio between FOXP3 positive regulatory T cell and interleukin‐17 secreting cell in renal allograft biopsies with acute T‐cell‐mediated rejection
- T‐Regulatory Cells in Human Transplantation
- The Role of Regulatory T cells in Kidney Transplantation
- Intragraft Regulatory T Cells in Protocol Biopsies Retain Foxp3 Demethylation and Are Protective Biomarkers for Kidney Graft Outcome
- Иммуномодулирующая активность мезенхимальных стромальных (стволовых) клеток
- Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs.
- Transient Low-Dose Methotrexate Induces Tolerance to Murine Anti-Thymocyte Globulin and Together They Promote Long-Term Allograft Survival
- Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients
Related papers
- Genentech taps Affimed’s antibodies
- KOMPLIKASI REGIONAL ANESTESI PADA PEDIATRIK
- Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria
- Cardiac retransplantation in children.
- PD-09.06: Third kidney transplants: surgical aspects
- Avaliacao hemodinamica sequencial em transplante de coracao
- Thoracoscopic discectomy and fusion in the treatment of spinal deformities
- [Hepatic retransplant and acute Budd Chiari syndrome. Case report].