The Latent Herpes Simplex Virus Type 1 Genome Copy Number in Individual Neurons Is Virus Strain Specific and Correlates with Reactivation

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Summary

This is the first demonstration that the number of HSV genome copies within individual latently infected neurons is regulated by viral genetic factors, and suggests that the latent genome copy number may be an important parameter for subsequent induced reactivation in vivo.

Type
article
Published
1998-07-01
Cited by
201
References
37
Access
Open access

Keywords

Biology, Herpes simplex virus, Virus latency, Virology, Genome

References

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