THE SERINE PROTEASE MATRIPTASE-2 (TMPRSS6) INHIBITS HEPCIDIN ACTIVATION BY CLEAVING MEMBRANE HEMOJUVELIN

Keywords

Hepcidin, TMPRSS6, Serine protease, Cell biology, Proteases

References

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• Defective Intracellular Trafficking of Uromodulin Mutant IsoformsIlenia Bernascone, Stefano Vavassori, Alessio Di Pentima — 2006
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• The epidermal barrier function is dependent on the serine protease CAP1/Prss8Céline Leyvraz, Roch‐Philippe Charles, Isabelle Rubera — 2005
• The Serine Protease TMPRSS6 Is Required to Sense Iron DeficiencyXin Du, Ellen She, Terri Gelbart — 2008
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• Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).Carole Peyssonnaux, Annelies S. Zinkernagel, Reto A. Schuepbach — 2007

Cited by

• The iron cycle in chronic kidney disease (CKD): from genetics and experimental models to CKD patients.Torsten Hitz — 2014
• Functional diversity of TMPRSS6 isoforms and variants expressed in hepatocellular carcinoma cell linesAdrián Margarit — 2018
• Modulation of hepcidin as therapy for primary and secondary iron overload disorders: pre-clinical models and approachesPaul J. Schmidt, Mark D. Fleming — 2014
• Exploring the Mechanisms by which Increasing Dietary Protein Induces Iron Transporter Expression and Improves Intestinal Iron AbsorptionCarrie Thomas — 2013
• Iron excretion in iron dextran-overloaded mice.Marco Musumeci, Sonia Maccari, Alessia Raffaella De Massimi — 2014
• Régulation de l'hepcidine et le rôle de la lipocaline 2 dans l'homéostasie du fer / Novel insights into the regulation of hepcidin and the role of lipocalin 2 in iron homeostasisHua Huang — 2014
• Roles Of Tea Consumption & Co-Fortification In Iron NutritionA. Beverly — 2012
• Inflammation neither increases hepatic hepcidin nor affects intestinal (59)Fe-absorption in two murine models of bowel inflammation, hemizygous TNF(ΔARE/+) and homozygous IL-10(-/-) mice.Marzell Buffler, Christiane Becker, W. Windisch — 2015
• A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortiumNicole Soranzo, Tim D. Spector, Massimo Mangino — 2009
• The Cutting Edge: Membrane Anchored Serine Protease Activities in the Pericellular MicroenvironmentToni Antalis, Marguerite S. Buzza, Kathryn M. Hodge — 2010
• DEVELOPMENT OF A MASS SPECTROMETRY DIAGNOSTIC ASSAY TO MONITOR HEPCIDIN LEVELS IN HEMOCHROMATOSIS PATIENTSChoon Lin — 2010
• Matriptase-2 and the biological behaviours of prostate cancer cells : a possible role for beta-cateninS. Webb — 2011
• The role of adipocytes in the modulation of iron metabolism in obesitySusana Coimbra, Cristina Catarino, Alice Santos‐Silva — 2013
• Repulsive Guidance Molecules (RGMs) and Neogenin in Bone Morphogenetic Protein (BMP) signalingChenxi Tian, Jun Liu — 2013
• The regulation of iron transportDavid M. Frazer, Gregory J. Anderson — 2014
• Is EPO therapy able to correct iron deficiency anaemia caused by matriptase‐2 deficiency?Gaël Nicolas, Jean‐Christophe Deschemin, Andrew Ramsay — 2011
• Iron-deficiency anemia.Clara Camaschella — 2015
• Relationship Between Iron and ErythropoiesisNadia Maria Sposi — 2012
• A Systems Biology Approach to Iron MetabolismJulia Chifman, Reinhard Laubenbacher, Suzy V. Torti — 2014
• Inhibitors of Matriptase‐2 Based on the Trypsin Inhibitor SFTI‐1Agata Gitlin‐Domagalska, Dawid Dębowski, Natalia Karna — 2015

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