Design & rationale of the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS).
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Summary
The inclusion of unstable angina in the primary end point to reflect the increasing trend to treat coronary heart disease aggressively before a myocardial infarction has occurred and may help clarify the role of aggressive LDL cholesterol reduction measures in primary prevention.
- Type
- article
- Published
- 1997-08-01
- Cited by
- 84
- References
- 23
- OpenAlex
- https://openalex.org/W2011739374
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42521979
Keywords
Medicine, Lovastatin, Placebo, Myocardial infarction, Unstable angina
References
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- Is relationship between serum cholesterol and risk of premature death from coronary heart disease continuous and graded? Findings in 356,222 primary screenees of the Multiple Risk Factor Intervention Trial (MRFIT).
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- Group sequential designs using a family of type I error probability spending functions.
- A simple approximation for calculating sample sizes for comparing independent proportions.
- The case for unstable angina pectoris as a primary end point in primary prevention studies.
- Cholesterol and mortality. 30 years of follow-up from the Framingham study.
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- Range of serum cholesterol values in the population developing coronary artery disease.
- Sheffield risk and treatment table for cholesterol lowering in prevention of coronary heart disease.
- Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.
- Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)
- Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms.
- Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease.
- Changing presentation of coronary heart disease in an inpatient population within the U.S. military health care system.
- Protocol for a prospective collaborative overview of all current and planned randomized trials of cholesterol treatment regimens. Cholesterol Treatment Trialists' (CTT) Collaboration.
Cited by
- Estimating the population impact of an intervention: a decision-analytic approach
- Do statins cause cancer? A meta-analysis of large randomized clinical trials.
- Pioglitazone for Secondary Prevention after Ischemic Stroke and Transient Ischemic Attack: Rationale and Design of the Insulin Resistance Intervention after Stroke (IRIS) Trial
- A tale of two trials: The West of Scotland Coronary Prevention Study and the Texas Coronary Atherosclerosis Prevention Study.
- Managing dyslipidemia in Turkey: suggested guidelines for a population characterized by low levels of high density lipoprotein cholesterol.
- Statins and fibrates for preventing melanoma.
- 1998 clinical practice guidelines for the management of diabetes in Canada. Canadian Diabetes Association.
- The Effect of Deployment on Cholesterol Levels of Active Duty Personnel
- Screening for cardiovascular disease. Concepts, conflicts, and consensus.
- The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases
- Statins for primary prevention of venous thromboembolism.
- Lability of serum low-density lipoprotein cholesterol levels during screening in subgroup of Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) cohort
- Estimating the long-term effects of storage at -70 degrees C on cholesterol, triglyceride, and HDL-cholesterol measurements in stored sera.
- Statins and cancer: A systematic review and meta-analysis.
- Diabetes, hyperlipidemia, and coronary artery disease.
- Statins and Intracerebral Hemorrhage: Collaborative Systematic Review and Meta-Analysis
- Low cholesterol and violent crime.
- Preventing Coronary Disease in Women: Brief Observations from the Clinical Data
- Effects of increasing high-density lipoprotein cholesterol and decreasing low-density lipoprotein cholesterol on the incidence of first acute coronary events (from the Air Force/Texas Coronary Atherosclerosis Prevention Study).
- Therapeutic modulation of low-density lipoprotein size
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