Polymeric implants for cancer chemotherapy.
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Summary
The principles of chemotherapy using polymer implants and injectable microspheres are reviewed, and recent preclinical and clinical studies of this new technology for treating cancer are summarized.
- Type
- article
- Published
- 1997-07-07
- Cited by
- 204
- References
- 109
- Access
- Open access
- OpenAlex
- https://openalex.org/W2011546003
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24134956
Keywords
Chemotherapy, Microsphere, Drug, Drug delivery, Medicine
References
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- Assumptions in the radiotherapy of glioblastoma
- Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain.
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- Controlled release, biodegradable cytokine depots: a new approach in cancer vaccine design.
- Reduction of systemic exposure and toxicity of cisplatin by encapsulation in poly-lactide-co-glycolide.
- Interstitial taxol delivered from a biodegradable polymer implant against experimental malignant glioma.
- Covalent coupling of methotrexate to dextran enhances the penetration of cytotoxicity into a tissue-like matrix.
- Transport of molecules in the tumor interstitium: a review.
- Distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants.
- Release of peptides from sustained delivery systems (microcapsules and microparticles) in vivo. A histological and immunohistochemical study.
- One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats.
- Interaction between diffusion and Michaelis-Menten uptake of dopamine after iontophoresis in striatum.
- THE USE OF SILICONE RUBBER AS A CARRIER FOR PROLONGED DRUG THERAPY.
- Novel systems for controlled delivery of macromolecules.
- In vivo characteristics of low molecular weight copolymers composed of L-lactic acid and various DL-hydroxy acids as biodegradable carriers for drug delivery systems.
- The intracerebral distribution of BCNU delivered by surgically implanted biodegradable polymers.
- Brain biocompatibility of a biodegradable controlled release polymer consisting of anhydride copolymer of fatty acid dimer and sebacic acid
Cited by
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- Nanoscale polymer carriers to deliver chemotherapeutic agents to tumours
- Delivery of Viral Vectors to Tumor Cells: Extracellular Transport, Systemic Distribution, and Strategies for Improvement
- Using Affinity To Provide Long-Term Delivery of Antiangiogenic Drugs in Cancer Therapy.
- Toxicities and therapeutic effect of 5-fluorouracil controlled release implant on tumor-bearing rats.
- Chemotherapy drug delivery from calcium phosphate nanoparticles
- Prevention and treatment of lung cancer by green tea polyphenols.
- Optimization of Novel Thermo-gelling Tri-block Co-polymeric Carriers for the Delivery of Paclitaxel for the Treatment Glioblastoma Multiforme
- NOVEL HYDROXYL TERMINATED DENDRIMERS AS POTENTIAL DRUG CARRIERS: SUSTAINED RELEASE, HEMOLYSIS AND CYTOTOXICITY STUDY
- Poly(lactide-co-glycolide) microspheres and hydrogel delivery systems for soft tissue and cartilage tissue engineering applications
- Application of Ultrasound Imaging for Noninvasive Characterization of Phase Inverting Implants
- Filmes de acetato de celulose/poli (caprolactona triol): diagrama de fases, propriedades térmicas, mecânicas e controle da permeação de um fármaco modelo
- Development, Characterization of Hydroxyl Terminated Dendritic Macromolecules as Prospective Drug Carriers
- Poly(ester-anhydride) for controlled delivery of hydrophilic drugs
- Reduction-sensitive polymeric nanocarriers in cancer therapy: a comprehensive review.
- Fluorine ion-implanted polystyrene improves growth and viability of vascular smooth muscle cells in culture.
- Gold half-shell coated hyaluronic acid-doxorubicin conjugate micelles for theranostic applications
- Preparation and characterization of biocompatible spongy cryogels of poly(vinyl alcohol)–gelatin and study of water sorption behaviour
- Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model
- Fabrication of biodegradable micelles with reduction-triggered release of 6-mercaptopurine profile based on disulfide-linked graft copolymer conjugate.
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