A simple method for studying the solubilization of polycyclic aromatic hydrocarbons in DNA solutions.
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Summary
The mononucleotide results suggest a binding preference of pyrene to purine bases and the solubility data for pyrene in the DNA solutions are interpreted in terms of the binding abilities of intercalative versus external sites and the effect of salt.
- Type
- article
- Published
- 1983-04-15
- Cited by
- 9
- References
- 7
- OpenAlex
- https://openalex.org/W2011520559
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:29229475
Keywords
Chemistry, Pyrene, DNA, Sodium dodecyl sulfate, Solubility
References
- Interaction between DNA and polycyclic aromatic hydrocarbons
- Activated metabolites of carcinogenic hydrocarbons
- Studies of the binding of actinomycin and related compounds to DNA.
- The Interaction of Polycyclic Hydrocarbons and Nucleic Acids
- Interaction of polynuclear aromatic hydrocarbons, 4‐nitroquinoline 1‐oxides, and various dyes with DNA
- Interactions of heteroaromatic compounds with nucleic acids. 1. The influence of heteroatoms and polarizability on the base specificity of intercalating ligands.
- PHYSICAL BINDING OF TETRAOLS DERIVED FROM 7,8-DIHYDROXY-9,10-EPOXYBENZO(A)PYRENE TO DNA
- Stereodynamics of Molecular Systems
Cited by
- Rates of hydrolysis and extents of DNA binding of 5-methylchrysene dihydrodiol epoxides.
- Induction of DNA‐Double‐Strand Breaks by Auger Electrons from 99mTc Complexes with DNA‐Binding Ligands
- Mechanisms underlying the impact of humic acids on DNA quantification by SYBR Green I and consequences for the analysis of soils and aquatic sediments.
- Standardized measurements and differential spectroscopy in microplates.
- Polycyclic aromatic hydrocarbons physically intercalate into duplex regions of denatured DNA.
- Synthesis of pyrene—acridine bis-intercalators and effects of binding to DNA
- Pyrene as a sensitive probe for DNA conformational changes due to protonation.
- Pyrenylboronic Acid as a Novel Entry for Photochemical DNA Cleavage
- Polycyclic aromatic hydrocarbon carcinogenicity: Theoretical modelling and experimental facts
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