Gene regulation for higher cells: a theory.
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Summary
Direct support for the idea that regulation of gene activity underlies cell differentiation comes from evidence that much of the genome in higher cell types is inactive and that different ribonucleic acids are synthesized in different cell types.
- Type
- article
- Published
- 1969-07-25
- Cited by
- 1,963
- References
- 65
- OpenAlex
- https://openalex.org/W2010916267
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:41722798
Keywords
Gene, Computational biology, Biology, Genetics, Cell biology
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- The Inheritance of Taillessness (Anury) in the House Mouse.
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- Altered Gene Expression during Differentiation : Population Changes in Hybridizable RNA after Stimulation of the Chick Oviduct with Oestrogen
- Ribonucleic acid and protein synthesis in ovary.
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- THE EFFECTS OF ESTRADIOL ON ACID MUCOPOLYSACCHARIDE METABOLISM IN OOPHORECTOMIZED RATS.
- Evidence for the appearance of novel gene products during amphibian blastulation.
- Organ-specific restriction of transcription in mammalian chromatin.
Cited by
- The APUD cell concept
- Zur Topochemie der Hormonwirkung
- Restriction site periodicities in highly repetitive DNA of primates.
- Cell polyploidy: its relation to tissue growth and function.
- Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells.
- Developmental genetics of homoeosis.
- Localization of chromosomal RNA in human G-banded metaphase chromosomes.
- Transcription of circular, single‐stranded DNA by maize RNA polymerase II
- A developmental handshake: neuronal control of ionic currents and their control of neuronal differentiation.
- The effect of infection with adenovirus 2 on the transcription of cellular RNA.
- D-RNA containing ribonucleoprotein particles.
- Highly repeated sequences in mammalian genomes.
- Regulation of the pattern of protein synthesis in Schizophyllum commune by the incompatibility genes.
- The influence of whole-arm trisomy on gene expression in Drosophila.
- Reverse transcriptase: Mediator of genomic plasticity
- RNAi – Is one suffix sufficient?
- Evolution of Biological Complexity
- Hairpin RNAs and Retrotransposon LTRs Effect RNAi and Chromatin-Based Gene Silencing
- The small RNA world of plants.
- A generative bias towards average complexity in artificial cell lineages
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