Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

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Summary

CD317 (also called BST2 or HM1), a membrane protein of previously unknown function, is identified as a tetherin andhibition of Vpu function and consequent mobilization of tetherin’s antiviral activity is a potential therapeutic strategy in HIV/AIDS.

Type
article
Published
2008-01-24
Cited by
1,967
References
22
Access
Open access

Keywords

Tetherin, Retrovirus, Cell biology, Cell, Biology

References

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