Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies
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Summary
In GBM patients cancer‐initiating cells contribute to the profound immune suppression that in turn correlated with CSCs STAT3 (CD133 + ), and further studies of microenvironment are needed to better understand the origin of GMB/GBM C SCs and its immunosuppressive properties.
- Type
- review
- Published
- 2010-07-01
- Cited by
- 114
- References
- 83
- OpenAlex
- https://openalex.org/W2010401946
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23681226
Keywords
Cancer stem cell, Cancer research, Tumor microenvironment, Stem cell, Cancer
References
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Cited by
- Dissolving heterogeneity in cancer
- Impact of genetic targets on primary brain tumor therapy: what's ready for prime time?
- LOW REACTIVE OXYGEN SPECIES AND HIGH GLYCOLYSIS IN GLIOBLASTOMA STEM CELLS:MECHANISMS AND THERAPEUTIC IMPLICATIONS
- Isolation, cultivation and identification of brain glioma stem cells by magnetic bead sorting
- Process of the Functional Reorganization of the Cortical Centers for Movement in GBM Patients: fMRI Study
- Gliometako zelula nestina-positiboen banaketa
- Radiation therapy for glioma stem cells.
- Stem Cell Biology in Neoplasms of the Central Nervous System
- Molekularna charakterystyka nowotworowych komórek macierzystych i progenitorowych rdzeniaka
- Large-Scale Production of Human Glioblastoma-Derived Cancer Stem Cell Tissue in Suspension Bioreactors to Facilitate the Development of Novel Oncolytic Therapeutics
- Quantum dot platform for single-cell molecular profiling
- Implications of mitogen‐activated protein kinase signaling in glioma
- Inhibition of Na+-K+-2Cl− cotransporter isoform 1 accelerates temozolomide-mediated apoptosis in glioblastoma cancer cells
- Deregulated MicroRNAs Identified in Isolated Glioblastoma Stem Cells: An Overview
- Methylation mediated silencing of miR-23b expression and its role in glioma stem cells.
- [Stem cells: implications in the development of brain tumors].
- The expression patterns of Msi1 related with the glioma grade and the cytoplasmic Msi1 promotes angiogenesis.
- Overview and recent advances in neuropathology. Part 1: Central nervous system tumours.
- A mesenchymal glioma stem cell profile is related to clinical outcome
- Chemokine CXCL12 in neurodegenerative diseases: a S.O.S signal for stem cell-based repair
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