Sporadic Pick's disease: A tauopathy characterized by a spectrum of pathological τ isoforms in gray and white matter
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Summary
Pick's disease is characterized by an accumulations of Pick bodies in the hippocampal region and cortex as well as the presence of three and four microtubule‐binding repeat τ pathology in both cortical gray and white matter that distinguish this tauopathy from other neurodegenerative disorders.
- Type
- article
- Published
- 2002-06-01
- Cited by
- 156
- References
- 45
- OpenAlex
- https://openalex.org/W2009925591
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24432739
Keywords
Tauopathy, Gene isoform, Tau protein, Microtubule, Pick's disease
References
- Neocortical morphometry and cholinergic neurochemistry in Pick's disease.
- Ageing and Dementia
- Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
- Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy
- Mass and physical dimensions of two distinct populations of paired helical filaments.
- Frontotemporal dementia, Pick disease, and corticobasal degeneration. One entity or 3? 1.
- Specific Pathological Tau Protein Variants Characterize Pick's Disease
- Structural analysis of Pick's disease-derived and in vitro-assembled tau filaments.
- Neuronal and glial DNA fragmentation in Pick’s disease
- Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.
- Pick’s disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment
- Pick's disease immunohistochemistry: new alterations and Alzheimer's disease comparisons
- The Classification, Genetics and Neuropathology of Frontotemporal Dementia. Introduction to the Special Topic Papers: Part I
- IMMUNOELECTRON MICROSCOPY OF ALZHEIMER AND PICK BRAIN TISSUE LABELLED WITH THE MONOCLONAL ANTIBODY ALZ–50
- Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease
- A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.
- From genotype to phenotype: A clinical, pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP‐17) caused by the P301L tau mutation
- Greenfield's Neuropathology.
- Pick's Disease: A Modern Approach
- Interlaboratory Comparison of Neuropathology Assessments in Alzheimer's Disease: A Study of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD)
Cited by
- Relationship between Frontotemporal Dementia and Corticobasal Degeneration/Progressive Supranuclear Palsy
- Cellular tau pathology and immunohistochemical study of tau isoforms in sporadic tauopathies
- 18F-flortaucipir uptake patterns in clinical subtypes of primary progressive aphasia.
- Differential Incorporation of Tau Isoforms in Alzheimer's Disease
- The role of chaperone proteins in neurodegenerative diseases
- The Levels of Tau Isoforms Containing Exon-2 and Exon-10 Segments Increased in the Cerebrospinal Fluids of the Patients with Sporadic Creutzfeldt-Jakob Disease
- Neuropathology of Pick body disease.
- Selective reduction of soluble Tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study
- Modificacions post-traduccionals de l'α-sinucleïna en les malalties neurodegeneratives
- Investigation of laser-microdissected inclusion bodies.
- Pathophysiology of the behavioral variant of frontotemporal lobar degeneration: A study combining MRI and FDG-PET
- Factors patogènics convergents en taupaties
- 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress.
- Neuropathology of non-Alzheimer degenerative disorders.
- Pathologie und Biochemie der frontotemporalen Demenzen
- Morphological alterations in frontotemporal dementia
- Invited review: Neuropathology of tauopathies: principles and practice
- Expression of transcription factors c-Fos, c-Jun, CREB-1 and ATF-2, and caspase-3 in relation with abnormal tau deposits in Pick’s disease
- Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity
- Acetylated tau neuropathology in sporadic and hereditary tauopathies.
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