Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

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Summary

Results indicate that apo A-I has an impaired ability to remove cholesterol and phospholipid from Tangier fibroblasts, possibly because of a defective interaction of apo B-I with cell-surface binding sites.

Type
article
Published
1995-07-01
Cited by
425
References
37
Access
Open access

Keywords

Tangier disease, Cholesterol, Apolipoprotein B, ABCA1, Sphingomyelin

References

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