Construction of an infectious Marek's disease virus bacterial artificial chromosome and characterization of protection induced in chickens.

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Summary

In vitro, the BAC-derived virus had similar biological characteristics and growth kinetics as the wild-type parental and recombinant viruses, and chickens immunized with BAC derivatives by various delivery mechanisms acquired protection against virulent MDV challenge.

Type
article
Published
2009-03-01
Cited by
22
References
29

Keywords

Biology, Virology, Bacterial artificial chromosome, Virus, Recombinant DNA

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