Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors.
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Summary
The KIT and MGF genes have been shown to play key roles in embryonal and postnatal development of germ cells and their expression was evaluated by Northern blot analysis in a panel of three GCT cell lines and 24 fresh GCT biopsies.
- Type
- article
- Published
- 1992-11-15
- Cited by
- 109
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W2006237067
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40624522
Keywords
Biology, Isochromosome, Loss of heterozygosity, Germ cell, Genetics
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