Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

Keywords

Dynamin, Mitochondrial fission, Cell biology, Biology, GTP'

References

• Visualization of dynamins.Jason A. Mears, Jenny E. Hinshaw — 2008
• The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeastWilliam Bleazard, J. Michael McCaffery, Edward J. King — 1999
• hFis1, a Novel Component of the Mammalian Mitochondrial Fission Machinery*Dominic I. James, Philippe A. Parone, Yves Mattenberger — 2003
• Three-dimensional reconstruction of dynamin in the constricted statePeijun Zhang, Jenny E. Hinshaw — 2001
• Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane CurvingHarry H. Low, Carsten Sachse, Linda Amos — 2009
• G domain dimerization controls dynamin's assembly-stimulated GTPase activityJoshua S. Chappie, Sharmistha Acharya, Marilyn Leonard — 2010
• Dynamin undergoes a GTP-dependent conformational change causing vesiculation.Sharon Sweitzer, Jenny E. Hinshaw — 1998
• The WD40 protein Caf4p is a component of the mitochondrial fission machinery and recruits Dnm1p to mitochondriaErik E. Griffin, Johannes Graumann, David C. Chan — 2005
• Structural basis of oligomerization in the stalk region of dynamin-like MxASong Gao, Alexander von der Malsburg, Susann Paeschke — 2010
• Identification of the binding site for acidic phospholipids on the pH domain of dynamin: implications for stimulation of GTPase activity.Jie Zheng, Sean M. Cahill, Mark A. Lemmon — 1996
• Real-time Visualization of Dynamin-catalyzed Membrane Fission and Vesicle ReleaseThomas J. Pucadyil, Sandra L. Schmid — 2008
• Functional partnership between amphiphysin and dynamin in clathrin-mediated endocytosisKohji Takei, Vladimir I. Slepnev, Volker Haucke — 1999
• GTP-dependent twisting of dynamin implicates constriction and tension in membrane fissionAurélien Roux, Katherine E. Uyhazi, Adam Frost — 2006
• Membrane fission: model for intermediate structures.Yonathan Kozlovsky, Michael M. Kozlov — 2003
• EMAN: semiautomated software for high-resolution single-particle reconstructions.Steven J. Ludtke, Philip R. Baldwin, Wah Chiu — 1999
• Rapid constriction of lipid bilayers by the mechanochemical enzyme dynamin.Dganit Danino, Kwan-Hoon Moon, Jenny E. Hinshaw — 2004
• Self-assembly of Human MxA GTPase into Highly Ordered Dynamin-like Oligomers*Georg Kochs, Markus Haener, Ueli Aebi — 2002
• A Model for Dynamin Self-assembly Based on Binding Between Three Different Protein Domains*Е. А. Смирнова, Dixie‐Lee Shurland, Erin Newman‐Smith — 1999
• The stalk region of dynamin drives the constriction of dynamin tubesYen-Ju Chen, Peijun Zhang, Edward H. Egelman — 2004
• Computer visualization of three-dimensional image data using IMOD.James R. Kremer, David N. Mastronarde, J. Richard McIntosh — 1996

Cited by

• Adapt and Divide: The Emerging Importance of Dynamin Adaptors in Mitochondrial FissionJohn D. McGregor — 2013
• Regulation of Mitochondrial Morphology by LipidsJack McFadden, J.R. Knepp — 2014
• MORPHOLOGICAL CONTROL OF MITOCHONDRIAL BIOENERGETICSYisang Yoon — 2015
• Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1Л. П. Вильчинская — 2015
• Membrane fission by protein crowdingG Amare, C. C. du Preez, B Taye — 2017
• Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Anna Matysek-Jędrych — 2017
• DYNAMIN-MEDIATED MEMBRANE FISSIONSandrine Morlot — 2012
• The mechanical bond: a work of art.Carson J. Bruns, J. Fraser Stoddart — 2012
• Investigation of the mitochondrial functions of proteins genetically associated with Parkinson's DiseaseV. Burchell — 2012
• Structure, regulation, and evolution of the plastid division machinery.Shin‐ya Miyagishima, Hiromitsu Nakanishi, Yukihiro Kabeya — 2011
• Mitochondrien als Kraftwerk der β-ZelleSimone Baltrusch, F Reinhardt, Markus Tiedge — 2015
• Does mitochondrial fusion require transmembrane potential?Iuliia Karavaeva, K. V. Shekhireva, Fedor F. Severin — 2015
• Use of a Novel Two Color PALM Method to Examine Structural Properties of Drp1 Helical Rings during Mammalian Mitochondrial Fission In Situ.Alyssa B. Rosenbloom — 2012
• Splitting up the powerhouse: structural insights into the mechanism of mitochondrial fissionViviane Richter, Abeer Prakash Singh, Marc Kvansakul — 2015
• Molecular Mechanisms of Mitochondrial Transport in NeuronsMiloš Babić — 2015
• The Role of ATAD3A and SLC25 Proteins in OPA1 FunctionJ. Wong — 2014
• Dynamic tubulation of mitochondria drives mitochondrial network formationChong Wang, Wanqing Du, Qian Peter Su — 2015
• Mitochondrial fusion and fission proteins: novel therapeutic targets for combating cardiovascular diseaseA R Hall, Niall Burke, R K Dongworth — 2014
• Mitochondrial protein quality control in health and diseaseMichael J. Baker, Catherine S. Palmer, Diana Stojanovski — 2014
• MECHANISMS FOR COUNTERING OXIDATIVE STRESS AND DAMAGE IN RETINAL PIGMENT EPITHELIUMScott M. Plafker, Gary B. O'Mealey, Luke I. Szweda — 2012

Related papers

• Auto‐inhibition of dynamin GTPase activity is regulated by PH domain interactionsJon Kenniston, Mark A. Lemmon — 2009
• GTP Concentration Bursts Locally at Endocytic Sites for Dynamin-Dependent Membrane FissonAisha Azhar, Yuuta Imoto, Shigeki Watanabe — 2019
• Dynamin GTPase, a force‐generating molecular switchDale E. Warnock, Sandra L. Schmid — 1996
• Ubiquitously expressed dynamin-II has a higher intrinsic GTPase activity and a greater propensity for self-assembly than neuronal dynamin-I.Dale E. Warnock, Takeshi Baba, Sandra L. Schmid — 1997
• Uncoupling of dynamin polymerization and GTPase activity revealed by the conformation-specific nanobody dynabValentina Galli, Rafael Sebastián, Sandrine Moutel — 2017
• Dynamin-Catalyzed Membrane Fission Requires Coordinated GTP HydrolysisYa‐Wen Liu, Juha-Pekka Mattila, Sandra L. Schmid — 2013
• The Appendage Domain of α-Adaptin Is a High Affinity Binding Site for Dynamin (*)Li-Hsien Wang, Thomas C. Südhof, Richard G.W. Anderson — 1995
• Dynamin Self-assembly Stimulates Its GTPase Activity*Dale E. Warnock, Jenny E. Hinshaw, Sandra L. Schmid — 1996
• Robust colorimetric assays for dynamin's basal and stimulated GTPase activities.Marilyn Leonard, Byeong Doo Song, Rajesh Ramachandran — 2005
• The GTPase effector domain sequence of the Dnm1p GTPase regulates self-assembly and controls a rate-limiting step in mitochondrial fission.N Fukushima, Ellen Brisch, Brian R. Keegan — 2001