Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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Summary

A unique cellular gene, CEM15, is described, whose transient or stable expression in cells that do not normally express CEM15 recreates this phenotype, but whose antiviral action is overcome by the presence of Vif.

Type
article
Published
2002-08-08
Cited by
558
References
58

Keywords

Biology, Virology, Infectivity, Viral replication, Phenotype

References

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