Evidence that cellular immune responses to soluble and membrane associated antigens are independently regulated during human schistosomiasis mansoni
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Summary
The hypothesis that the response to adult worm antigens may be pivotal in determining both the development of resistance and severity of disease is supported.
- Type
- article
- Published
- 1996-02-01
- Cited by
- 19
- References
- 84
- OpenAlex
- https://openalex.org/W2001055320
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:20605003
Keywords
Antigen, Biology, Immune system, Immunology, Schistosoma mansoni
References
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- Delayed hypersensitivity granuloma formation around Schistosoma mansoni eggs in vitro. I. Definition of the model.
- Failure of immunosuppressive mechanisms in human Schistosoma mansoni infection with hepatosplenomegaly
- Dichotomies in the reactivity to worm antigen in human schistosomiasis mansoni.
- Sm25, a major schistosome tegumental glycoprotein, is dependent on palmitic acid for membrane attachment.
- Protein measurement with the Folin phenol reagent.
- Immunological studies in human schistosomiasis. III. Immunoglobulin levels, antibodies, and delayed hypersensitivity.
- Immunity after treatment of human schistosomiasis: association between cellular responses and resistance to reinfection
- γ‐interferon treatment inhibits collagen deposition in murine schistosomiasis
- Immunity after treatment of human schistosomiasis: association between IgE antibodies to adult worm antigens and resistance to reinfection
- Evidence for an association between human resistance to Schistosoma mansoni and high anti‐larval IgE levels
- Antigen‐Presenting Function of B Lymphocytes
- Protective immunization of mice against Schistosoma mansoni with purified adult worm surface membranes
- Leukocytes of patients with Schistosoma mansoni respond with a Th2 pattern of cytokine production to mitogen or egg antigens but with a Th0 pattern to worm antigens.
- Analysis of antibody responses of Schistosoma mansoni infected patients against schistosomal antigens.
- Fibrogenic cytokines: the role of immune mediators in the development of scar tissue.
- Immunity in filariasis: perspectives for vaccine development.
Cited by
- Schistosomal granuloma modulation
- High levels of TNF, soluble TNF receptors, soluble ICAM-1, and IFN-gamma, but low levels of IL-5, are associated with hepatosplenic disease in human schistosomiasis mansoni.
- An Immunomics Approach to Schistosome Antigen Discovery: Antibody Signatures of Naturally Resistant and Chronically Infected Individuals from Endemic Areas
- Stage-specific immune responses in human Necator americanus infection
- Cytokine secretion profile associated with periportal fibrosis in S. mansoni-infected Egyptian patients
- Cytokines, chemokine receptors, CD4+CD25HIGH+ T-cells and clinical forms of human schistosomiasis.
- Schistosomal granuloma modulation. I. Schistosoma mansoni worm antigens CAA and CCA prime egg-antigen-induced hepatic granuloma formation
- T and B cell reactivity to a 42-kDa protein is associated with human resistance to both schistosomiasis mansoni and haematobium.
- Schistosomal granuloma modulation. II. Specific immunogenic carbohydrates can modulate schistosome-egg-antigen-induced hepatic granuloma formation
- Cellular responses to Loa loa experimental infection in mandrills (Mandrillus sphinx) vaccinated with irradiated infective larvae
- CD4+ T Cells of Schistosomiasis Naturally Resistant Individuals Living in an Endemic Area Produce Interferon‐γ and Tumour Necrosis Factor‐α in Response to The Recombinant 14kdaSchistosoma mansoni Fatty Acid‐Binding Protein
- Differential antigen‐stimulated proliferation of human mononuclear cells by recombinant Schistosoma japonicum antigens in a Chinese population
- Current Status of Vaccines for Schistosomiasis
- Cross-Reactivity of Schistosoma mansoni Cytosolic Superoxide Dismutase, a Protective Vaccine Candidate, with Host Superoxide Dismutase and Identification of Parasite-Specific B Epitopes
- Clinical and immunologic evaluation of 31 patients with acute schistosomiasis mansoni.
- Human Immune Responses to Schistosoma mansoni Vaccine Candidate Antigens
- Blood Fluke Exploitation of Innate-Adaptive Immune Interactions to Facilitate Parasite Development
- Investigating the inflammatory markers involved in Schistosoma haematobium protective immunity and susceptibility to infection
- Vaccines Against Schistosomiasis
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