Niche and neutral effects of acquired immunity permit coexistence of pneumococcal serotypes
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Summary
It is shown that weak serotype-specific immunity and an acquired response not specific to the capsule can together reproduce observed diversity, which can be used to explain the effects of pneumococcal vaccination and indicates general factors that regulate the diversity of pathogens.
- Type
- article
- Published
- 2012-03-01
- Cited by
- 177
- References
- 73
- OpenAlex
- https://openalex.org/W1999399962
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25192564
Keywords
Serotype, Biology, Streptococcus pneumoniae, Immunity, Immunology
References
- Stability of Serotypes during Nasopharyngeal Carriage of Streptococcus pneumoniae
- Prevalence of nasopharyngeal antibiotic-resistant pneumococcal carriage in children attending private paediatric practices in Johannesburg.
- Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus isolated from the nasopharynx of healthy children attending day-care centres in the Czech Republic
- Serotype distribution and antimicrobial resistance patterns of nasopharyngeal and invasive Streptococcus pneumoniae isolates in Hong Kong children.
- Phenotypic and Genotypic Characterization of Streptococcus pneumoniae Strains Colonizing Children Attending Day-Care Centers in Norway
- Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model.
- Use of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in Pakistan for surveillance for antimicrobial resistance
- The Limiting Similarity, Convergence, and Divergence of Coexisting Species
- Nasopharyngeal Carriage of Streptococcus pneumoniae in Gambian Children who Participated in a 9-valent Pneumococcal Conjugate Vaccine Trial and in Their Younger Siblings
- Chaos, persistence, and evolution of strain structure in antigenically diverse infectious agents.
- Vaccination against colonizing bacteria with multiple serotypes.
- Estimation of vaccine efficacy against acquisition of pneumococcal carriage.
- Streptococcus pneumoniae and Haemophilus influenzae type b Carriage, Central Asia
- An epidemic of complex dysmorphologic syndromes in southeast Spain?
- The dynamics of nasopharyngeal streptococcus pneumoniae carriage among rural Gambian mother-infant pairs
- Nasopharyngeal Carriage of Streptococcus pneumoniae in Navajo and White Mountain Apache Children Before the Introduction of Pneumococcal Conjugate Vaccine
- Effect of reduced-dose schedules with 7-valent pneumococcal conjugate vaccine on nasopharyngeal pneumococcal carriage in children: a randomized controlled trial.
- Effect of Pneumococcal Conjugate Vaccination on Serotype-Specific Carriage and Invasive Disease in England: A Cross-Sectional Study
- No coexistence for free: Neutral null models for multistrain pathogens
- The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi District, Kenya
Cited by
- Age-Dependent Prevalence of Nasopharyngeal Carriage of Streptococcus pneumoniae before Conjugate Vaccine Introduction: A Prediction Model Based on a Meta-Analysis
- Relationship between nasopharyngeal carriage and acute otitis media due to Streptococcus pneumoniae among Finnish children aged less than two years
- Prevalence and load of airway bacteria in chronic obstructive pulmonary disease
- Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae
- Secular trends (1990-2013) in serotypes and associated non-susceptibility of S. pneumoniae isolates causing invasive disease in the pre-/post-era of pneumococcal conjugate vaccines in Spanish regions without universal paediatric pneumococcal vaccination.
- Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children
- Competition, coinfection and strain replacement in models of Bordetella pertussis.
- How direct competition shapes coexistence and vaccine effects in multi-strain pathogen systems.
- Pneumococcal Capsules and Their Types: Past, Present, and Future
- Ecology of zoonoses: natural and unnatural histories
- Comparative analysis of Streptococcus pneumoniae transmission in Portuguese and Finnish day-care centres
- Exploring individual HPV coinfections is essential to predict HPV-vaccination impact on genotype distribution: a model-based approach.
- Differences in serious clinical outcomes of infection caused by specific pneumococcal serotypes among adults.
- Linking data and models: The importance of statistical analyses to inform models for the transmission dynamics of infections
- Five challenges in evolution and infectious diseases.
- Antibiotic resistance as collateral damage: the tragedy of the commons in a two-disease setting
- The community ecology of pathogens: coinfection, coexistence and community composition.
- Pathogen diversity and hidden regimes of apparent competition
- Genetic conjugation of components in two pneumococcal fusion protein vaccines enhances paediatric mucosal immune responses.
- Controlled human infection and rechallenge with Streptococcus pneumoniae reveals the protective efficacy of carriage in healthy adults.
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