Mechanisms of the origin of chromosomal aberrations.
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Summary
Heterogeneity regarding the induction of initial DNA lesions and their repair among chromosomes or regions of the same chromosome, ratio between symmetrical and asymmetrical exchanges, influence of DNA repeats, chromatin condensation and cell-cycle checkpoints on the formation of chromosome alterations are discussed.
- Type
- article
- Published
- 1998-08-03
- Cited by
- 20
- References
- 40
- OpenAlex
- https://openalex.org/W1999181780
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42861652
Keywords
Chromatin, Chromosome, Biology, DNA, Genetics
References
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- Recent developments in the assessment of chromosomal damage.
- Cytogenetic damage and the radiation-induced G1-phase checkpoint.
- The accurate estimation of chromatid breakage, and its relevance to a new interpretation of chromatid aberrations induced by ionizing radiations
- Localization of chromosome breakpoints induced by AluI and BamHI in Chinese hamster ovary cells treated in the G1 phase of the cell cycle.
- Potentiation of bleomycin by the aminothiol WR-1065 in assays for chromosomal damage in G0 human lymphocytes.
- The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations.
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- Mechanisms of chromosomal aberration production. II. Aberrations induced by 5-bromodeoxyuridine and visible light.
- Analysis of naturally occurring and radiation-induced breakpoint locations in human chromosomes 1, 2 and 4.
- Analysis of the distribution of DNA repair patches in the DNA-nuclear matrix complex from human cells.
- Analysis of restriction enzyme-induced chromosome aberrations in the interstitial telomeric repeat sequences of CHO and CHE cells by FISH.
- Mechanisms of chromosomal aberration production. I. Aberration induction by ultraviolet light.
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- Antimutagenic Effect of Origanum majorana L. Essential Oil Against Prallethrin-Induced Genotoxic Damage in Rat Bone Marrow Cells
- Evaluation of radionuclide induced damage in marine invertebrates
- Interaction effects of 5-azacytidine with topoisomerase II inhibitors on CHO cells, as detected by cytogenetic analysis.
- Mechanisms of clastogen-induced chromosomal aberrations: a critical review and description of a model based on failures of tethering of DNA strand ends to strand-breaking enzymes.
- Chromosomal Aberrations in Lymphocytes of Healthy Subjects and Risk of Cancer
- Fenvalerate-induced chromosome aberrations and sister chromatid exchanges in the bone marrow cells of mice in vivo.
- Reproduction impairment following paternal genotoxin exposure in brown trout (Salmo trutta) and Arctic charr (Salvelinus alpinus).
- Age-related changes in radiation-induced micronuclei among healthy adults.
- Assessment of the ability of Imazaquin herbicide to induce chromosomal aberrations in vitro in cultured Chinese hamster ovary cells and micronuclei in vivo in mice.
- Chromosomal Aberrations in Cord Blood Are Associated with Prenatal Exposure to Carcinogenic Polycyclic Aromatic Hydrocarbons
- Fluorescence in situ hybridization is necessary to detect an association between chromosome aberrations and polycyclic aromatic hydrocarbon exposure in utero and reveals nonrandom chromosome involvement
- Genotoxic Effects of Catha edulis (Khat) Extract on Mice Bone Marrow Cells
- The detection of genetic toxicity in marine organisms
- DNA damage in the kidney tissue cells of the fish Rhamdia quelen after trophic contamination with aluminum sulfate
- Genotoxic evaluation of synthetic hydroxyapatite using mammalian bone marrow chromosome aberration test
- Effect of diterpenoid kaurenoic acid on genotoxicity and cell cycle progression in gastric cancer cell lines.
- Avaliação do potencial citotóxico das lectinas de Canavalia ensiformis, Canavalia brasiliensis e Cratylia floribunda
- Assessment of Genotoxic and Cytogenetic Effects of Aflatoxin B1 in Mouse Bone Marrow Cells
- Jordan Journal of Biological Sciences (JJBS)
- Chromosomal Aberration Test Utilities In Vitro and In Vivo
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