Cytogenetic damage and the radiation-induced G1-phase checkpoint.

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Summary

The results suggest that the presence of a well-defined p53-dependent G1-phase arrest does not reduce chromosomal aberrations caused by low doses of ionizing radiation markedly, but may reduce the overall degree of survival by triggering other G 1-phase events.

Type
article
Published
1996-03-01
Cited by
47
References
32

Keywords

G2-M DNA damage checkpoint, Mitosis, DNA damage, Biology, Cell cycle checkpoint

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