Linkage Disequilibrium: Ancient History Drives the New Genetics

Keywords

Linkage disequilibrium, Disequilibrium, Genetic association, Biology, Association mapping

References

• Nonuniform recombination within the human beta-globin gene cluster.B. S. Weir, William G. Hill — 1986
• Linkage disequilibrium predicts physical distance in the adenomatous polyposis coli region.Lynn B. Jorde, W. Scott Watkins, M. Carlson — 1994
• High-resolution haplotype structure in the human genomeMark J. Daly, John D. Rioux, S. F. Schaffner — 2001
• Y chromosome sequence variation and the history of human populationsPeter A. Underhill, Peidong Shen, Alice Lin — 2000
• Use of population isolates for mapping complex traitsLeena Peltonen, Aarno Palotie, Kenneth Lange — 2000
• Haplotype tagging for the identification of common disease genesGillian C.L. Johnson, Laura Esposito, Bryan J. Barratt — 2001
• THE CONTROL OF THE FALSE DISCOVERY RATE IN MULTIPLE TESTING UNDER DEPENDENCYYoav Benjamini, Daniel Yekutieli — 2001
• Intensely punctate meiotic recombination in the class II region of the major histocompatibility complexAlec J. Jeffreys, Liisa Kauppi, Rita Neumann — 2001
• Statistical significance for genomewide studiesJohn D. Storey, Robert Tibshirani — 2003
• A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus.Cyrus P. Zabetian, George Anderson, Sarah G. Buxbaum — 2001
• The HLA system and the analysis of multifactorial genetic disease.Ian Tomlinson, Walter F. Bodmer — 1995
• Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex diseaseDavid Botstein, Neil Risch — 2003
• Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies.Frank Dudbridge, Bobby P. C. Koeleman — 2004
• Coalescent-Based Association Mapping and Fine Mapping of Complex Trait LociSebastian Zöllner, Jonathan K. Pritchard — 2005
• Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humansChristopher S. Carlson, Michael A. Eberle, Mark J. Rieder — 2003
• Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium.Christopher S. Carlson, Michael A. Eberle, Mark J. Rieder — 2004
• Linkage disequilibrium in the human genomeDavid Reich, Michele Cargill, Stacey Bolk — 2001
• Patterns of polymorphism and linkage disequilibrium suggest independent origins of the human growth hormone gene cluster.Aravinda Chakravarti, J A Phillips, Kenneth H. Mellits — 1984
• Sum statistics for the joint detection of multiple disease loci in case‐control association studies with SNP markersAnja Wille, Josephine Hoh, Jürg Ott — 2003
• Genotyping over 100,000 SNPs on a pair of oligonucleotide arraysHajime Matsuzaki, Shoulian Dong, Halina Loi — 2004

Cited by

• Characterization of the genetic structure of the azorean populationCláudia Margarida Aguiar, C. Branco — 2007
• Estimating recombination rates from genetic variation in humans.Adam Auton, Gil McVean — 2012
• Quantitative Approaches to Understanding Cancer Genomes.Michele C. Gornick — 2011
• TNFRSF13B Genetic variability an anthropological - evolutionary approach to Biomedical ResearchMarco Sazzini — 2009
• On the Time Scale of Human Evolution: Evidence for Recent Adaptive EvolutioGerhard Meisenberg — 2008
• "Genes for Intelligence": A Review of Recent ProgressGerhard Meisenberg — 2005
• Investigating candidate genes identified by genome-wide studies of granulomatous diseases in susceptibility to tuberculosis: ANXA11 and the CADM familyMuneeb Salie — 2010
• Human genetic susceptibility to tuberculosis : the investigation of candidate genes influencing interferon gamma levels and other candidate genes affecting immunological pathwaysM. Moller — 2007
• Homozygosity, inbreeding and health in European populationsRuth McQuillan — 2009
• Genetic landscape of the people of India: a canvas for disease gene explorationSamir K. Brahmachari — 2008
• Computer simulation of marker-assisted selection utilizing linkage disequilibrium.Sarah Keildson — 2006
• Investigation into natural variation and adaptation of arabidopsis thaliana in Edinburgh and the LothiansP. Lim — 2013
• Runs of Homozygosity: Association with Coronary Artery Disease and Gene Expression in Monocytes and Macrophages.Paraskevi Christofidou, Christopher P. Nelson, Majid Nikpay — 2015
• Genes of the serotonergic system & susceptibility to psychiatric disorders : A gene-based haplotype approachGhazal Zaboli — 2006
• Linkage disequilibrium of evolutionarily conserved regions in the human genomeMamoru Kato, Akihiro Sekine, Yozo Ohnishi — 2006
• Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom.Sarah L. Spain, Jean‐Baptiste Cazier, Richard S. Houlston — 2009
• No Association Between Cholinergic Muscarinic Receptor 2 (CHRM2) Genetic Variation and Cognitive Abilities in Three Independent SamplesPenelope A. Lind, Michelle Luciano, Michael A. Horan — 2009
• Variants in DNA double‐strand break repair and DNA damage‐response genes and susceptibility to lung and head and neck cancersPatrick Danoy, Stefan Michiels, Philippe Dessen — 2008
• Association mapping for growth, straightness and wood chemistry traits in the Pinus pinaster Aquitaine breeding populationCamille Lepoittevin, Luc Harvengt, Christophe Plomion — 2012
• Colorectal cancer risk is not associated with increased levels of homozygosity in Saudi ArabiaAbdul K. Siraj, Hanif Khalak, Mehar Sultana — 2012

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• Gametic disequilibrium and physical distance.Carlos Zapata, G. Visedo — 1995
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