The role of lipid peroxidation and antioxidants in oxidative modification of LDL.
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Summary
A comprehensive survey on the compositional properties of LDL relevant for its susceptibility to oxidation, on the mechanism and kinetics of LDL oxidation, and on the chemical and physico-chemical properties of HDL oxidized by exposure to copper ions is provided.
- Type
- review
- Published
- 1992-10-01
- Cited by
- 2,306
- References
- 292
- OpenAlex
- https://openalex.org/W1997745709
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19170832
Keywords
Lipid peroxidation, Chemistry, Biochemistry, Oxidative phosphorylation, Apolipoprotein B
References
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- Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.
- Autoxidation of unsaturated lipids
- The interaction of carbamylated low-density lipoprotein with cultured cells. Studies with human fibroblasts, rat peritoneal macrophages and human monocyte-derived macrophages.
- A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein.
- HDL-cholesterol, apolipoproteins A1 and B. Age and index body weight.
- Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells.
- Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis.
Cited by
- Discovery and characterization of inflammation-induced electrophilic fatty acid derivatives
- Antioxidant vitamin-cardiovascular disease hypothesis is still promising, but still unproven: the need for randomized trials.
- The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.
- Analysis of F2-isoprostanes as indicators of non-enzymatic lipid peroxidation in vivo by gas chromatography-mass spectrometry: development of a solid-phase extraction procedure.
- Vitamin E reverses cholesterol-induced endothelial dysfunction in the rabbit coronary circulation.
- Antioxidant Action of Carotenoids in Vitro and in Vivo and Protection against Oxidation of Human Low‐Density Lipoproteins a , b
- Carbamylation of proteins and atherogenesis in renal failure.
- The potential of antioxidants to prevent atherosclerosis development and its clinical manifestations.
- Decreased susceptibility to copper‐induced oxidation of rat‐lipoproteins after fibrate treatment: influence of fatty acid composition
- Oxidative damage and fibrogenesis.
- Susceptibility of VLDL to oxidation in patients on regular haemodialysis.
- Endothelial cell monolayer dysfunction caused by oxidized low density lipoprotein: attenuation by oleic acid.
- Epidemiological studies on antioxidants, lipid peroxidation and atherosclerosis.
- Action of vitamin E as antioxidant against oxidative modification of low density lipoprotein
- Are Uremia, Diabetes, and Atherosclerosis Linked With Impaired Antioxidant Mechanisms?
- Cellular oxidation of low-density lipoprotein by Chlamydia pneumoniae.
- Oxidized high-density lipoprotein induces neuron death.
- Calcium and lipoprotein lipase synergistically enhance the binding and uptake of native and oxidized LDL in mouse peritoneal macrophages.
- Inhibitory Effect of Isoflavones on Peroxynitrite-mediated Low-density Lipoprotein Oxidation
- Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein.
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