Effects of anthrapyrazole antineoplastic agents on lipid peroxidation.

Keywords

Lipid peroxidation, Chemistry, Microsome, Biochemistry, Pharmacology

References

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• Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.Evan D. Kharasch, Raymond Novak — 1985
• Anthrapyrazoles, a new class of intercalating agents with high-level, broad spectrum activity against murine tumors.Wilbur R. Leopold, James M. Nelson, Jacqueline Plowman — 1985
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• The anthracycline antineoplastic drugs.Robert C. Young, Robert F. Ozols, Charles E. Myers — 1981
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• Oxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complex.Charles E. Myers, Luca Gianni, Charles B. Simone — 1982
• Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation.Edward G. Mimnaugh, Michael A. Trush, Theodore E. Gram — 1981
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• Oxidative destruction of DNA by the adriamycin-iron complex.Helen M. Eliot, Luca Gianni, Charles E. Myers — 1984
• Design, biochemical pharmacology, electrochemistry and tumour biology of anti-tumour anthrapyrazoles.Hollis D. Showalter, David W. Fry, W R Leopold — 1986
• Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.Nicholas R. Bachur, Sandra Gordon, Malcolm V. Gee — 1977

Cited by

• Peroxidase induced metabolism and lipid peroxide scavenging by antitumor agents.Paweł Kołodziejczyk, J. William Lown — 1990
• The effect of the anthrapyrazole antitumour agent CI941 on rat liver microsome and cytochrome P-450 reductase mediated free radical processes. Inhibition of doxorubicin activation in vitro.Martin A. Graham, David R. Newell, John Butler — 1987
• Phase I study of high-dose piroxantrone with granulocyte colony-stimulating factor.Diane Savarese, Andrea Denicoff, Stacey L. Berg — 1993
• Comparison of the chronic toxicity of piroxantrone, losoxantrone and doxorubicin in spontaneously hypertensive rats.Eugene H. Herman, Jun Zhang, Brian B. Hasinoff — 1998
• Phase I pharmacokinetic study of DUP-937, a new anthrapyrazoleKarl Bélanger, Jacques Jolivet, Jean A. Maroun — 1993
• The displacement of iron(III) from its complexes with the anticancer drugs piroxantrone and losoxantrone by the hydrolyzed form of the cardioprotective agent dexrazoxane.Brian B. Hasinoff, Khanh Tran — 1999
• Status of new anthrapyrazole and pyrazoloacridine derivatives.Stacey L. Berg — 1996
• The pharmacokinetics and toxicity of the anthrapyrazole anti-cancer drug CI-941 in the mouse: a guide for rational dose escalation in patientsMartinA. Graham, DavidR. Newell, BrendaJ. Foster — 2004
• The ability of new formamidine sugar-modified derivatives of daunorubicin to stimulate free radical formation in three enzymatic systems: NADH dehydrogenase, NADPH cytochrome P450 reductase and xanthine oxidase.Jolanta Pawłowska, Jolanta Tarasiuk, Edward Borowski — 2000
• A multicenter phase II trial of losoxantrone (DuP-941) in hormone-refractory metastatic prostate cancer.S. Huan, Ronald B. Natale, DJ Stewart — 2000
• Phase I pharmacokinetic and pharmacodynamic study of a new anthrapyrazole, CI-937 (DUP937).Charles Erlichman, Malcolm J. Moore, Ian G. Kerr — 1991
• PHOTOSENSITIZATION OF NEOPLASTIC CELLS BY ANTHRAPYRAZOLES *David Kessel — 1988
• The anthrapyrazoles: a new class of compounds with clinical activity in breast cancer.Ian Judson — 1992
• Navelbine and the anthrapyrazoles.Alison L. Jones, Ian E. Smith — 1994
• Interaction of topoisomerase II-targeted anticancer agents with the doxorubicin cardioprotective drug dexrazoxane, and synthesis of a dexrazoxane analogK. Tran — 1999
• Cellular and Molecular Pharmacology of the Anthrapyrazole Antitumour AgentsL. H. Patterson, D. Newell — 1994

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