Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals.
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- Type
- article
- Published
- 1994-07-15
- Cited by
- 2,283
- References
- 40
- OpenAlex
- https://openalex.org/W1996413533
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:38513201
Keywords
Cyclin-dependent kinase, Biology, Cyclin A, CDK inhibitor, Cyclin D
References
- Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15.
- A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII
- Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.
- Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents.
- An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.
- Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.
- Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
- G1 events and regulation of cell proliferation.
- p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.
- Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
- Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
- A cell cycle regulator potentially involved in genesis of many tumor types.
- Cyclin-dependent regulation of G1 in mammalian fibroblasts.
- Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells.
- Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.
- WAF1, a potential mediator of p53 tumor suppression.
- Mammalian G1 cyclins.
- Activation of human cyclin-dependent kinases in vitro.
- Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.
- FAR1 links the signal transduction pathway to the cell cycle machinery in yeast.
Cited by
- Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1.
- The effects of cell adhesion on the growth and protein productivity of animal cells
- Inhibitors of cyclin-dependent kinase and cancer
- Inactivation of cyclin-dependent kinase inhibitor genes and development of human acute leukemias.
- WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases
- Opposite Transcriptional Effects of Cyclic AMP-Responsive Elements in Confluent or p27KIP-Overexpressing Cells versus Serum-Starved or Growing Cells
- The role of cyclin E in cell proliferation, development and cancer.
- Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities.
- Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells
- p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry
- A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells.
- Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6.
- Rapid induction of p21WAF1 but delayed down-regulation of Cdc25A in the TGF-β-induced cell cycle arrest of gastric carcinoma cells
- GROWTH OF MDA‐MB‐231 CELL LINE: DIFFERENT EFFECTS OF TGF‐β1, EGF AND ESTRADIOL DEPENDING ON THE LENGTH OF EXPOSURE
- Myc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway
- Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity
- P21 and Retinoblastoma Protein Control the Absence of DNA Replication in Terminally Differentiated Muscle Cells
- Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: implications for Beckwith-Wiedemann syndrome.
- Inhibition of cell growth and apoptosis by inducible expression of the transcriptional repressor Mad1.
- Inhibition of Vascular Smooth Muscle Cell Proliferation by Sodium Salicylate Mediated by Upregulation of p21Waf1 and p27Kip1
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