Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.

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Summary

Results indicate that phosphorylation of LIM-kinase by ROCK and consequently increased phosphorylated of cofilin by LIM- Kinase contribute to Rho-induced reorganization of the actin cytoskeleton.

Type
article
Published
1999-08-06
Cited by
1,736
References
19

Keywords

Cofilin, Cell biology, Rho-associated protein kinase, PAK1, Phosphorylation

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