EGF–ERBB signalling: towards the systems level

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Summary

It is useful to envision ERBB signalling as a bow-tie-configured, evolvable network, which shares modularity, redundancy and control circuits with robust biological and engineered systems.

Type
review
Published
2006-07-01
Cited by
2,073
References
145

Keywords

Signalling, ErbB, Robustness (evolution), Systems biology, Signalling pathways

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