Viral vectored immunocontraception: screening of multiple fertility antigens using murine cytomegalovirus as a vaccine vector.
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Summary
The partial infertility seen in mice infected with one of the polyepitope vaccines is a promising finding suggesting that it may be possible to combine a species specific virus with aspecies specific antigen for use as a disseminating mouse control agent.
- Type
- article
- Published
- 2007-01-08
- Cited by
- 20
- References
- 50
- OpenAlex
- https://openalex.org/W1994214968
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26043972
Keywords
Biology, Antigen, Virology, Zona pellucida, Infertility
References
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- Mouse-specific immunocontraceptive polyepitope vaccines.
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- Regulation of the Class II MHC Pathway in Primary Human Monocytes by Granulocyte-Macrophage Colony-Stimulating Factor 1
- Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation.
- Identification and characterization of a G protein-coupled receptor homolog encoded by murine cytomegalovirus
- B-cell activation following murine cytomegalovirus infection: implications for autoimmunity.
- Phase I study in cancer patients of a replication-defective avipox recombinant vaccine that expresses human carcinoembryonic antigen.
- Targeting of EBNA1 for Rapid Intracellular Degradation Overrides the Inhibitory Effects of the Gly-Ala Repeat Domain and Restores CD8+ T Cell Recognition*
- Biology of Attenuated Modified Vaccinia Virus Ankara Recombinant Vector in Mice: Virus Fate and Activation of B- and T-Cell Immune Responses in Comparison with the Western Reserve Strain and Advantages as a Vaccine
- The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes.
- Vaccination of Mice with Bacteria Carrying a Cloned Herpesvirus Genome Reconstituted In Vivo
- Association of oviduct-specific glycoproteins with human and baboon (Papio anubis) ovarian oocytes and enhancement of human sperm binding to human hemizonae following in vitro incubation.
- Effect of a null mutation of the oviduct-specific glycoprotein gene on mouse fertilization.
- Murine polyubiquitin mRNA sequence.
- Maximizing antigen targeting to the proteasome for gene-based vaccines.
- Genetic Live Vaccines Mimic the Antigenicity But Not Pathogenicity of Live Viruses
- Murine cytomegalovirus IE2, an activator of gene expression, is dispensable for growth and latency in mice.
- Murine cytomegalovirus infection-induced polyclonal B cell activation is independent of CD4+ T cells and CD40.
Cited by
- Current ZP3-based immunocontraceptive vaccine for free ranging wild pest.
- Mechanisms of virally vectored immunocontraception
- In vivo and in vitro studies of 4-vinylcyclohexene diepoxide in wild-caught female brushtail possums (Trichosurus vulpecula) and Norway rats (Rattus norvegicus) and its potential as a fertility control agent
- Immunocontraception in mice using repeated, multi‐antigen peptides: immunization with purified recombinant antigens
- Promoter control over foreign antigen expression in a murine cytomegalovirus vaccine vector.
- Nanotechnology in vaccine delivery
- Overcoming innate host resistance to vaccination: employing a genetically distinct strain of murine cytomegalovirus avoids vector-mediated resistance to virally vectored immunocontraception.
- Is there a role for immunocontraception?
- Prospects for virally vectored immunocontraception in the control of wild house mice (Mus domesticus)
- Controlling animal populations using anti-fertility vaccines.
- Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection
- Development of a conditionally-attenuated cytomegalovirus (CMV) vaccine vector platform, and initial investigations into use of CMV as a vaccine against pandemic influenza A virus
- Plant-Produced Mouse-Specific Zona Pellucida 3 Peptide Induces Immune Responses in Mice
- Exploring the Potential of Cytomegalovirus-Based Vectors: A Review
- The Quest for Immunity: Exploring Human Herpesviruses as Vaccine Vectors
- Plant-produced mouse zona pellucida 3 peptide, its immunogenicity and contraceptive efficacy
- Cytomegalovirus-based vaccine expressing Ebola virus Cytomegalovirus-based vaccine expressing Ebola virus glycoprotein protects nonhuman primates from Ebola virus glycoprotein protects nonhuman primates from Ebola virus infection infection
- Organ system Target Male Female Hypothalamic – pituitary axis Gonadotrophs Gonadotrophs Gonads Germ cell Ovarian follicle Sertoli cell Oocyte Leydig cell Granulosa cell
- Viral Infections of Laboratory Mice
- Immunocontraception in Wildlife Animals
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