The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells
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Summary
It is shown in a mouse autoimmune model that local Mrp8 and Mrp14 production is essential for the induction of autoreactive CD8+ T cells and the development of systemic autoimmunity.
- Type
- article
- Published
- 2010-06-01
- Cited by
- 307
- References
- 30
- OpenAlex
- https://openalex.org/W1993517541
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205386984
Keywords
Autoimmunity, Immunology, Downregulation and upregulation, CD8, Receptor
References
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- Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis
Cited by
- Proteome analysis of biological fluids from autoimmune‐rheumatological disorders
- S100A9 Knockout Decreases the Memory Impairment and Neuropathology in Crossbreed Mice of Tg2576 and S100A9 Knockout Mice Model
- The New Insight into the Role of Antimicrobial Proteins-Alarmins in the Immunopathogenesis of Psoriasis
- Involvement of S100A8/A9-TLR4-NLRP3 Inflammasome Pathway in Contrast-Induced Acute Kidney Injury
- Amyloids here, amyloids there…What’s wrong with them?
- Pathophysiology of chronic rhinosinusitis, pharmaceutical therapy options
- The Roles of S100A8 and S100A9 in Cartilage: Degradation and Formation
- S100A9-induced release of interleukin (IL)-6 and IL-8 through toll-like receptor 4 (TLR4) in human periodontal ligament cells.
- Elevated expressions of myeloid-related proteins-8 and -14 are danger biomarkers for lupus nephritis
- S100/calgranulins EN-RAGEing the blood vessels: implications for inflammatory responses and atherosclerosis
- Biomarkers for Refractory Lupus Nephritis: A Microarray Study of Kidney Tissue
- Estudo da estrutura e parceiros proteicos de proteínas codificadas por genes de micro-exons de Schistosoma mansoni
- On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets
- Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8
- Autoinflammation und Autoimmunität
- Trial Watch
- Cell-type-resolved quantitative proteomics of murine liver.
- CD4+ T cell-released exosomes inhibit CD8+ cytotoxic T-lymphocyte responses and antitumor immunity
- Predictive Significance of Kidney Myeloid-Related Protein 8 Expression in Patients with Obesity- or Type 2 Diabetes-Associated Kidney Diseases
- Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.
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