Dot1 and Histone H3K79 Methylation in Natural Telomeric and HM Silencing

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Summary

The results show that the commonly used URA3 reporter located at TEL-VIIL or at the mating loci may not report on natural PEV and that studies concerning the epigenetic mechanism of silencing in yeast should employ assays that report on the natural pattern of gene expression.

Type
article
Published
2011-04-08
Cited by
122
References
40
Access
Open access

Keywords

URA3, Biology, Gene silencing, DNA methylation, Methylation

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