S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast

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Summary

Sld2, one of the replication proteins of budding yeast, is phosphorylated in S phase in an S-Cdk-dependent manner, and mutant Sld2 lacking all the preferred Cdk phosphorylation sites (All-A) is defective in chromosomal DNA replication.

Type
article
Published
2002-02-07
Cited by
242
References
30

Keywords

Budding yeast, Cell biology, DNA replication, Control of chromosome duplication, DNA re-replication

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