Cells and Biomaterials for Intervertebral Disc Regeneration
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Summary
While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP), recent emphasis has been on the importance of restoring normal spine biomechanics and preventing degeneration of adjacent tissues.
- Type
- article
- Published
- 2010-07-12
- Cited by
- 27
- References
- 367
- OpenAlex
- https://openalex.org/W1989540171
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:71535879
Keywords
Regeneration (biology), Intervertebral disc, Materials science, Anatomy, Cell biology
References
- Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: An in vitro and in vivo experimental study
- Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy
- Evaluation of polymer scaffolds to be used in a composite injectable system for intervertebral disc tissue engineering.
- Mesenchymal stem cells avoid allogeneic rejection
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- Experimental Intervertebral Disc Regeneration with Tissue-Engineered Composite in a Canine Model
- Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc.
- Intervertebral Disc Cells Exhibit Differences in Gene Expression in Alginate and Monolayer Culture
- X-ray diffraction studies of the arrangement of collagenous fibres in human fetal intervertebral disc.
- Biochemistry of the intervertebral disc.
- Fibril-associated collagens.
- Recent Advances in Disc Cell Biology
- Low-intensity pulsed ultrasound stimulates cell proliferation, proteoglycan synthesis and expression of growth factor-related genes in human nucleus pulposus cell line.
- Clinical experience in cell-based therapeutics: disc chondrocyte transplantation A treatment for degenerated or damaged intervertebral disc.
- Artificial intervertebral discs and beyond: a North American Spine Society Annual Meeting symposium.
- Aging and degeneration of the human intervertebral disc.
- Intradiscal application of hyaluronic acid in the non-human primate lumbar spine: radiological results
- The influence of Matrigel or growth factor reduced Matrigel on human intervertebral disc cell growth and proliferation.
- Evaluation of Various Scaffolds for Tissue Engineered Biodisc Using Annulus Fibrosus Cells
Cited by
- Role of hypoxia and growth and differentiation factor-5 on differentiation of human mesenchymal stem cells towards intervertebral nucleus pulposus-like cells.
- Diversity of intervertebral disc cells: phenotype and function
- Self-assembling biomimetic hydrogels with bioadhesive properties for tissue engineering applications
- CELL THERAPY FOR INTERVERTEBRAL DISC REPAIR: ADVANCING CELL THERAPY FROM BENCH TO CLINICS
- Neural Network Analysis Identifies Scaffold Properties Necessary for In Vitro Chondrogenesis in Elastin-like Polypeptide Biopolymer Scaffolds
- Delivery systems for the treatment of degenerated intervertebral discs.
- Differentiation of Rodent Bone Marrow Mesenchymal Stem Cells into Intervertebral Disc-like Cells Following Coculture with Rat Disc Tissue
- Role of biomechanics on intervertebral disc degeneration and regenerative therapies: What needs repairing in the disc and what are promising biomaterials for its repair?
- Hydrostatic Pressure in Articular Cartilage Tissue Engineering: From Chondrocytes to Tissue Regeneration
- Advancing the cellular and molecular therapy for intervertebral disc disease.
- Injectable thermoreversible hyaluronan-based hydrogels for nucleus pulposus cell encapsulation
- Thermoreversible hyaluronan-based hydrogel supports in vitro and ex vivo disc-like differentiation of human mesenchymal stem cells.
- Biomimetic fibrin-hyaluronan hydrogels for nucleus pulposus regeneration.
- CHALLENGES AND STRATEGIES IN THE REPAIR OF RUPTURED ANNULUS FIBROSUS
- Multipotent Mesenchymal Stem Cell Treatment for Discogenic Low Back Pain and Disc Degeneration
- Development of an ex vivo cavity model to study repair strategies in loaded intervertebral discs
- Self-Healing Dynamic Hydrogel as Injectable Shock-Absorbing Artificial Nucleus Pulposus.
- Non-invasive Raman Spectroscopy and Quantitative Real-Time PCR Distinguish Among Undifferentiated Human Mesenchymal Stem Cells and Redifferentiated Nucleus Pulposus Cells and Chondrocytes In Vitro
- Isolation of high‐quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization
- Critical aspects and challenges for intervertebral disc repair and regeneration—Harnessing advances in tissue engineering
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