The effects of GABAB agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat

Explore this paper's citation graph

Summary

Examination of the effects of a novel GABAB agonist in models of chronic neuropathic and inflammatory pain in the rat and its inhibitory action on spinal transmission in vitro indicates that CGP35024 and L‐baclofen modulate nociceptive transmission in the spinal cord to inhibit neuropathic hyperalgesia, and that C GP35024 has a therapeutic window for antihyperalgesIA over spasmolysis.

Type
article
Published
2001-02-01
Cited by
214
References
56

Keywords

Baclofen, Gabapentin, Neuropathic pain, Hyperalgesia, Pharmacology

References

Cited by

Related papers