The impact of microRNAs on protein output
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Summary
The impact of micro RNAs on the proteome indicated that for most interactions microRNAs act as rheostats to make fine-scale adjustments to protein output.
- Type
- article
- Published
- 2008-07-30
- Cited by
- 3,808
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W1988163167
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2434960
Keywords
microRNA, Messenger RNA, Psychological repression, Proteome, Untranslated region
References
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- Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
- Identification of Human microRNA Targets From Isolated Argonaute Protein Complexes
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
- The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution
- Principles of MicroRNA–Target Recognition
- A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis.
- Enhanced analysis of metastatic prostate cancer using stable isotopes and high mass accuracy instrumentation.
- Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
- Pericellular mobilization of the tissue-destructive cysteine proteinases, cathepsins B, L, and S, by human monocyte-derived macrophages.
- Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.
- Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution.
- Introducing RefSeq and LocusLink: curated human genome resources at the NCBI.
- Human MicroRNA Targets
- The microRNA.org resource: targets and expression
- Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs
- Combinatorial microRNA target predictions
Cited by
- Analisi di espressione di microRNA in Tumore a Cellule Giganti: identificazione dei target con ruolo di potenziali biomarcatori
- Ancient roles of non-coding RNAs in eukaryotic evolution
- Cell cycle regulation by microRNAs in stem cells.
- Exploiting Drosophila genetics to understand microRNA function and regulation
- Induction de l'expression génique par des petits ARN dans des cellules de mammifère
- MicroRNA expression profiles predictive of human renal allograft status
- Tissue and Process Specific microRNA–mRNA Co-Expression in Mammalian Development and Malignancy
- Microrna-221 and Microrna-222 Modulate Differentiation and Maturation of Skeletal Muscle Cells
- Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
- Control of autocrine and paracrine myocardial signals: an emerging therapeutic strategy in heart failure
- Plasma microRNA 499 as a biomarker of acute myocardial infarction.
- microRNA Biogenesis and Function : An overview.
- Structural and quantitative proteomic analyses of argonaute2-containing ribonucleoprotein complexes
- In vivo delivery of cytoplasmic RNA virus-derived miRNAs.
- Determination of MiRNA Targets in Skeletal Muscle Cells
- MicroRNA-1 is a candidate tumor suppressor and prognostic marker in human prostate cancer
- Polypyrimidine Tract Binding Protein (hnRNP I) Is Possibly a Conserved Modulator of miRNA-Mediated Gene Regulation
- Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2
- MicroRNAs and Their Target Genes in Gingival Tissues
- MicroRNAs and autoimmunity
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