Cell–matrix adhesion
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Summary
This mini review discusses the roles of matrix properties such as composition, three‐dimensionality, and porosity, the bi‐directional functions of cellular contractility and matrix rigidity, and cell signaling in the formation of cell adhesions, assembly of matrix, migration, and tumorigenesis and speculates on the application of this knowledge to potential future therapeutic approaches.
- Type
- review
- Published
- 2007-12-01
- Cited by
- 1,019
- References
- 97
- Access
- Open access
- OpenAlex
- https://openalex.org/W1986411839
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45837997
Keywords
Extracellular matrix, Cell biology, Integrin, Fibronectin, Cell adhesion
References
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- Redox-dependent downregulation of Rho by Rac
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- Lysyl oxidase mediates hypoxic control of metastasis.
- Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5.
- Sensing the environment: a historical perspective on integrin signal transduction
- Cell migration at a glance
- Fibronectin at a glance
- Lysyl oxidase: an oxidative enzyme and effector of cell function
- FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness.
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- YAP-regulation of dynamic cell behaviour underlying organogenesis
- The role of the haemodynamic Palladin protein within the Vasculature
- Flightless I regulates hemidesmosome formation and integrin-mediated cellular adhesion and migration during wound repair.
- The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer
- The third type III module of human fibronectin mediates cell adhesion and migration.
- Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures
- Collagen gel three-dimensional matrices combined with adhesive proteins stimulate neuronal differentiation of mesenchymal stem cells
- New Insights into Vinculin Function and Regulation
- Mathematical modelling of cancer invasion: implications of cell adhesion variability for tumour infiltrative growth patterns.
- Mmp1 and Mmp2 cooperatively induce Drosophila fat body cell dissociation with distinct roles
- Role of tenascins in the ECM of gliomas
- Paris Saponin VII Inhibits the Migration and Invasion in Human A549 Lung Cancer Cells
- Extracorporeal shock waves trigger tenogenic differentiation of human adipose-derived stem cells
- Priming stem cells with protein kinase C activator enhances early stem cell-chondrocyte interaction by increasing adhesion molecules
- Phenotypic stability of the human MG‐63 osteoblastic cell line at different passages
- High-throughput Human Cell Reprogramming through Substrate and Microfluidics Integration
- Focal adhesion kinase, a major regulator of oligodendrocyte morphological maturation and myelination
- Hyaluronan-based pericellular matrix: substrate electrostatic charges and early cell adhesion events.
- Application of a human bone engineering platform to an in vitro and in vivo breast cancer metastasis model
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