Maternal toxicity and the identification of inorganic arsenic as a developmental toxicant.
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Summary
It is concluded that maternal and developmental toxicity occur in the same dose range for this potent cytotoxicant, although differential no observed adverse effect levels can be identified depending on the endpoints used.
- Type
- review
- Published
- 1994-07-01
- Cited by
- 39
- References
- 58
- OpenAlex
- https://openalex.org/W1986109831
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2074944
Keywords
Toxicant, Developmental toxicity, Toxicity, Arsenic toxicity, Hazard analysis
References
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- Prioritizing candidate reproductive/developmental toxicants for evaluation.
- Arsenic-induced exencephaly in the mouse and associated lesions occurring during neurulation.
- Maternal toxicity: a possible etiological factor in embryo-fetal deaths and fetal malformations of rodent-rabbit species.
- Role of maternal toxicity in assessing developmental toxicity in animals: a discussion.
- The concentration and chemical status of arsenic in the early placentas of arsenate-dosed hamsters.
- The teratogenic potential of cacodylic acid in the rat and mouse.
- Distribution, metabolism, and fetal uptake of pentavalent arsenic in pregnant mice following oral or intraperitoneal administration.
- The teratogenic profile of sodium arsenate in the golden hamster.
- Arsine: absence of developmental toxicity in rats and mice.
- Effects in the mouse and rat of prenatal exposure to arsenic
- Effects of prenatal arsenite exposure in the hamster
- Chemically induced alterations in maternal homeostasis and histology of conceptus: their etiologic significance in rat fetal anomalies.
- Metabolism of 74As-labeled trivalent and pentavalent inorganic arsenic in mice.
- The role of metallothionein induction and altered zinc status in maternally mediated developmental toxicity: comparison of the effects of urethane and styrene in rats.
Cited by
- Arsenic levels in the soil and risk of birth defects: a population-based case-control study using GIS technology.
- Selection of Test Chemicals for the ECVAM International Validation Study on In Vitro Embryotoxicity Tests
- An assessment of the developmental toxicity of inorganic arsenic.
- Influence of maternal restraint stress on arsenic-induced pre- and postnatal alterations in mice
- The effects of arsenic exposure on the nervous system.
- Chronic arsenic exposure and risk of infant mortality in two areas of Chile.
- Chronic exposure to mercuric chloride during gestation affects sensorimotor development and later behaviour in rats.
- FETAX Interlaboratory Validation Study: Phase III–Part 1 Testing
- Effects of sodium arsenite exposure on development and behavior in the rat.
- Reversibility of changes in brain cholinergic receptors and acetylcholinesterase activity in rats following early life arsenic exposure
- Influence of maternal stress on the effects of prenatal exposure to methylmercury and arsenic on postnatal development and behavior in mice: a preliminary evaluation.
- Association between Chronic Arsenic Exposure and Nutritional Status among the Women of Child Bearing Age: A Case-Control Study in Bangladesh
- Developmental and reproductive toxicity of inorganic arsenic: animal studies and human concerns.
- Influence of maternal stress on metal-induced pre- and postnatal effects in mammals
- Developmental toxicity of metal chelating agents.
- Arsenic affects on cerebellar development of mice
- Factors influencing arsenic methylation in humans
- Induction of Endogenous Nrf2/Small Maf Heterodimers by Arsenic-Mediated Stress in Placental Choriocarcinoma Cells
- Teratogen update: inorganic arsenic.
- Seminal Plasma Metals Concentration with Respect to Semen Quality
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