Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
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Summary
A sequence motif is identified that confers exosomal targeting to micro-RNAs and a ribonucleoprotein complex plays a role in this process and is identified as a key player in miRNA sorting into exosomes.
- Type
- article
- Published
- 2013-12-20
- Cited by
- 1,856
- References
- 52
- Access
- Open access
- OpenAlex
- https://openalex.org/W1985844219
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18239119
Keywords
Microvesicles, microRNA, Heterogeneous nuclear ribonucleoprotein, SUMO protein, Cell biology
References
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Cited by
- Urinary exosomes join the fight against infection.
- Characterization of miR-888 expression and regulation in endometrial cancer
- Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles.
- Differential fates of biomolecules delivered to target cells via extracellular vesicles
- Role of Exosomal Noncoding RNAs in Lung Carcinogenesis
- MEX3C interacts with adaptor-related protein complex 2 and involves in miR-451a exosomal sorting
- Cardioprotection by cardiac progenitor cell-secreted exosomes: role of pregnancy-associated plasma protein-A
- MicroRNAs, Regulatory Messengers Inside and Outside Cancer Cells.
- Stability of Circulating Exosomal miRNAs in Healthy Subjects
- RNA-Binding Proteins in Amyotrophic Lateral Sclerosis
- Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases
- Trimester-specific Plasma Exosome microRNA Expression Profiles in Preeclampsia
- Mechanisms associated with biogenesis of exosomes in cancer
- Investigating the Role of Exosomal Communication in the Glioma Microenvironment
- Extracellular vesicles shuffling intercellular messages: for good or for bad.
- Exosome Trafficking in the Acute Myeloid Leukemia Microenvironment
- Extracellular vesicles as new pharmacological targets to treat atherosclerosis.
- Molecular Details and Functional Analysis of RNA Binding by ESCRT-II
- Carcinogenic activity of PbS quantum dots screened using exosomal biomarkers secreted from HEK293 cells
- Exosomal Non-Coding RNAs: Diagnostic, Prognostic and Therapeutic Applications in Cancer
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