Renal SDF-1 signals mobilization and homing of CXCR4-positive cells to the kidney after ischemic injury.
Explore this paper's citation graph
Summary
The data show that renal SDF-1 is a currently unrecognized mediator of homing to and migration of CXCR4 expressing cells in the injured kidney, and suggest that S DF-1 may be a major signal involved in kidney repair.
- Type
- article
- Published
- 2005-05-01
- Cited by
- 404
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W1984974003
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19643095
Keywords
Homing (biology), Kidney, Bone marrow, Renal stem cell, Stromal cell
References
- Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
- Cloning and Relative Expression Analysis of Rat Stromal Cell Derived Factor-1 (SDF-1): SDF-1 α mRNA Is Selectively Induced in Rat Model of Myocardial Infarction
- CD34 expression by murine hematopoietic stem cells mobilized by granulocyte colony-stimulating factor.
- Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon
- Efficacious immunomodulatory activity of the chemokine stromal cell-derived factor 1 (SDF-1): local secretion of SDF-1 at the tumor site serves as T-cell chemoattractant and mediates T-cell-dependent antitumor responses.
- Active movement of T cells away from a chemokine
- Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
- Can stem cells cross lineage boundaries?
- Microvascular endothelial injury and dysfunction during ischemic acute renal failure.
- Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells ‘hide out’ in the bone marrow
- Cellular responses to hypoxia after renal segmental infarction.
- Purification and characterization of mouse hematopoietic stem cells.
- Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene.
- Chemokine receptor CXCR4 downregulated by von Hippel–Lindau tumour suppressor pVHL
- Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
- Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells.
- Bone marrow-derived progenitor cells in pulmonary fibrosis.
- Highly abundant genes in the transcriptosome of human and baboon CD34 antigen-positive bone marrow cells.
- Chemokine Receptors in Human Endothelial Cells
- Endothelial progenitor cells for postnatal vasculogenesis.
Cited by
- The application of stem cells in the treatment of ischemic diseases.
- Hepatic injury and the kinetics of bone marrow-derived hepatocyte transgene expression.
- Renal capsule as a stem cell niche.
- Disparate Companions: Tissue Engineering Meets Cancer Research
- MIF, CD74 and other partners in kidney disease: tales of a promiscuous couple.
- Mechanisms and consequences of injury and repair in older organ transplants
- Ultrasound-targeted stromal cell-derived factor-1-loaded microbubble destruction promotes mesenchymal stem cell homing to kidneys in diabetic nephropathy rats
- Ischemia-Reperfusion Injury Reduces Long Term Renal Graft Survival: Mechanism and Beyond
- Neural stem cell therapy for subacute and chronic ischemic stroke
- Stromal Cell-Derived Factor-1 Receptor CXCR4-Overexpressing Bone Marrow Mesenchymal Stem Cells Accelerate Wound Healing by Migrating into Skin Injury Areas
- ENDOLYN SORTING AND FUNCTION DURING KIDNEY DEVELOPMENT
- The role of CD248+ stromal cells in the pathogenesis of renal fibrosis
- The recruitment mechanisms and beneficial roles of haematopoietic stem cells in murine acute kidney injury
- Physiological and pathological consequences of identification of very small embryonic like (VSEL) stem cells in adult bone marrow.
- Early Detection of Heterotopic Ossification for Effective Prevention and Treatment
- In Situ Tissue Regeneration: Chemoattractants for Endogenous Stem Cell Recruitment
- Probing the sensitivity of autoantibody production to B cell depletion by Rituximab
- Pleiotropic effects of erythropoietin
- Myocyte-specific overexpression of stromal cell-derived Factor 1 facilitates cardiac regeneration and improves myocardial function after infarction in mice.
- Amélioration de la prise de greffe hématopoïétique par une thérapie cellulaire à base de cellules souches mésenchymateuses
Related papers
- Homing in hematopoietic stem cells: focus on regulatory role of CXCR7 on SDF1a/CXCR4 axis
- Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot Study
- Modulating the Interaction of Stromal-cell-derived Factor-1/CXCL12 and its Receptor, CXCR4, for Enhanced Mobilisation, Homing and Engraftment of Haematopoietic Stem Cells
- Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF‐1/CXCR4 axis toward enhancing the efficacy of stem cells' homing
- 2020 - GPRASP FAMILY MEMBERS REGULATE MURINE HEMATOPOIETIC STEM CELL MIGRATION, HOMING AND NICHE RETENTION POST-TRANSPLANT VIA CONTROL OF CXCR4 STABILITY
- Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice
- CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells
- Therapeutic Potential of CXCR4/SDF-1 Axis in Acute Myocardial Infarction
- Differential CXCR4 expression on hematopoietic progenitor cells versus stem cells directs homing and engraftment