Letrozole Therapy Alone or in Sequence with Tamoxifen in Women with Breast Cancer
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Summary
Among postmenopausal women with endocrine-responsive breast cancer, sequential treatment with letrozole and tamoxifen, as compared with letrozole monotherapy, did not improve disease-free survival.
- Type
- article
- Published
- 2009-08-20
- Cited by
- 507
- References
- 29
- Access
- Open access
- OpenAlex
- https://openalex.org/W1982866065
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19638490
Keywords
Letrozole, Tamoxifen, Medicine, Aromatase inhibitor, Breast cancer
References
- Switching to anastrozole after tamoxifen improves survival in postmenopausal women with breast cancer
- NCCN Task Force Report: Adjuvant Therapy for Breast Cancer.
- Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial.
- Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial.
- A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer.
- Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials.
- Should aromatase inhibitors be used as initial adjuvant treatment or sequenced after tamoxifen?
- Design, conduct, and analyses of Breast International Group (BIG) 1-98: A randomized, double-blind, phase-III study comparing letrozole and tamoxifen as adjuvant endocrine therapy for postmenopausal women with receptor-positive, early breast cancer
- Aromatase inhibitors versus tarnoxifen as adjuvant therapy for postmenopausal women with estrogen receptor positive breast cancer: meta-analyses of randomized trials of monotherapy and switching strategies
- Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxifen: the ARNO 95 Study.
- Stopping treatment can reverse acquired resistance to letrozole.
- Predictors of early relapse in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial.
- A Class of K-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk
- A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer*
- A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer.
- Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial.
- Statistics in medicine--reporting of subgroup analyses in clinical trials.
- Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis.
- The 38th David A. Karnofsky lecture: the paradoxical actions of estrogen in breast cancer--survival or death?
- Optimizing adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer: a decision analysis.
Cited by
- Intravenous bisphosphonates for breast cancer: Impact on patient outcomes and scientific concepts
- Breast cancer risk assessment in a mammography screening program and participation in the IBIS-II chemoprevention trial
- Neoadjuvant endocrine therapy for breast cancer.
- Women and Bone Health: Maximizing the Benefits of Aromatase Inhibitor Therapy
- Comparing guidelines for adjuvant endocrine therapy in postmenopausal women with breast cancer: a coming of age
- Systemic treatment of early breast cancer—a biological perspective
- Hormonal therapy for recurrent low-grade serous carcinoma of the ovary or peritoneum
- Recommendations for antiresorptive therapy in postmenopausal patients with breast cancer: Marburg AIBL Guideline Evaluation Study (MAGES)
- A review of the treatment of endocrine responsive metastatic breast cancer in postmenopausal women.
- Aetiology, genetics and prevention of secondary neoplasms in adult cancer survivors
- Tamoxifen benefits and CYP2D6 testing in women with hormone receptor-positive breast cancer.
- Effects of tamoxifen and aromatase inhibitors on breast tissue enhancement in dynamic contrast-enhanced breast MR imaging: a longitudinal intraindividual cohort study.
- Optimal approach in early breast cancer: Adjuvant and neoadjuvant treatment
- Estradiol suppresses phosphorylation of ERα serine 167 through upregulation of PP2A in breast cancer cells.
- Regulation of Matrix Metallopeptidase-1 in Breast Cancer Metastasis
- Personalized adjuvant therapies: lessons from the past: the opening address by the St. Gallen 2013 award recipient.
- 2012 Nams/Pfizer- Wulf H. Utian Endowed Lecture The scientific rationale for a delay after menopause in the use of conjugated equine estrogens in postmenopausal women that causes a reduction in breast cancer incidence and mortality
- Intratumoral estrogen sulfotransferase induction contributes to the anti-breast cancer effects of the dithiocarbamate derivative TM208
- Expression of CD24 and CD44 in breast cancer cells after cytotoxic drug exposure
- Znaczenie inhibitorów aromatazy w leczeniu chorych na raka piersi
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