Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.
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Summary
The findings demonstrate that antigen-induced proliferation is mediated through an autocrine pathway involving endogenous IL-2 production, release, and subsequent binding to IL-3-Ti receptor cross-linking.
- Type
- article
- Published
- 1984-03-01
- Cited by
- 473
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1980793481
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7536729
Keywords
Autocrine signalling, Receptor, Biology, Interleukin 2, Major histocompatibility complex
References
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Cited by
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