Early events in lymphocyte activation triggered via CD3/Ti or CD2.
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Summary
In recent years considerable insight has been gained into the sequence of events necessary for activation of lymphocytes, allowing the definition of several surface molecules of lymphocyte which can transmit signals to the cell and a variety of biochemical events which occur following ligand binding.
- Type
- article
- Published
- 1987-01-01
- Cited by
- 1
- References
- 24
- OpenAlex
- https://openalex.org/W100275791
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37470914
Keywords
Monoclonal antibody, Cell biology, Ligand (biochemistry), CD3, Lymphocyte
References
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- Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells
- Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.
- Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.
- A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor
- Tumor promoter phorbol esters induce unresponsiveness to antigen and expression of interleukin 2 receptor on T cells
- The role of protein kinase C in cell surface signal transduction and tumour promotion
- Phorbol myristic acetate stimulates LAF production by the macrophage cell line, P388D.
- An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
- An improved rosetting assay for detection of human T lymphocytes.
- Investigation of early T cell activation: Analysis of the effect of specific antigen, interleukin 2 and monoclonal antibodies on intracellular free calcium concentration
- Distinctive functional characteristics of human „T”︁ lymphocytes defined by E rosetting or a monoclonal anti‐T cell antibody
- Two monoclonal antibodies identifying a subset of human peripheral mononuclear cells with natural killer cell activity
- Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor
- Interleukin 2 regulates its own receptors.
- Monoclonal Antibodies for Analysis of the HLA System
- Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) pathways of human T-cell activation.
- Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen- receptor complex
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